CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Clinical trials for CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY explained in plain language.
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Tiny balloon tested to clear Life-Threatening heart blockages
Disease control CompletedThis study tested a very small balloon catheter called Sapphire 3. Doctors used it to gently open long-term, completely blocked heart arteries before placing a stent. Researchers watched 170 patients to see if the device was safe and worked well during the procedure and for 24 ho…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: OrbusNeich • Aim: Disease control
Last updated Apr 02, 2026 02:40 UTC
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Placebo vs procedure: the battle for chest pain relief
Symptom relief CompletedThis study tested whether a specific heart artery procedure (called CTO PCI) could reduce chest pain (angina) more effectively than a placebo procedure in patients already taking the best available medications. Fifty patients with a long-term blockage in a heart artery were rando…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: Mid and South Essex NHS Foundation Trust • Aim: Symptom relief
Last updated Apr 02, 2026 02:41 UTC
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Researchers track why heart stents fail years later
Knowledge-focused CompletedThis study aimed to learn how often and why stents re-narrow years after being placed to open a completely blocked heart artery. Researchers followed 294 patients for at least three years after their procedure, using heart scans to check the stents. The goal was to identify which…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: Lauri Mansikkaniemi • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC