CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Clinical trials for CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY explained in plain language.
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Can a vibrating wire reopen completely blocked heart arteries?
Disease control CompletedThis trial tests a new device designed to help doctors reopen coronary arteries that are completely blocked, a condition called chronic total occlusion. The device makes the tip of a guidewire vibrate at high frequency, which may help it safely cross the tough, fibrous cap of the…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: Shanghai MicroPort Rhythm MedTech Co., Ltd. • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New balloon device shows promise in clearing hardened heart blockages
Disease control CompletedThis study tested a very small balloon catheter (Sapphire 3) in 170 people with severely blocked heart arteries (chronic total occlusions). The balloon was used to open the blockage before placing a stent. The main goal was to see if the device could be safely delivered, inflated…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: OrbusNeich • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Heart procedure put to the test: placebo surgery reveals true benefits for chest pain
Symptom relief CompletedThis study tested whether a procedure to open a fully blocked heart artery (CTO PCI) actually reduces chest pain in people with stable angina. Fifty patients received either the real procedure or a placebo procedure, while all continued their usual heart medications. The goal was…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: Mid and South Essex NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Heart stent study reveals long-term narrowing risks after complex artery procedure
Knowledge-focused CompletedThis completed study looked at 294 patients who had a procedure to open a completely blocked heart artery (CTO PCI) with a drug-coated stent. Researchers wanted to know how often the stents narrowed again over at least three years and what factors increased that risk. The study u…
Matched conditions: CHRONIC TOTAL OCCLUSION OF CORONARY ARTERY
Phase: NA • Sponsor: Lauri Mansikkaniemi • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC