CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP)
Clinical trials for CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP) explained in plain language.
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Can a new injection shrink nasal polyps and restore easy breathing?
Disease control Not yet recruitingThis trial is testing an experimental drug called AK139, given as an injection, in people with chronic sinusitis and nasal polyps—growths in the nose that block airflow. The study compares AK139 against a placebo, with all participants also using a standard steroid nasal spray. T…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP)
Phase: PHASE2 • Sponsor: Akeso • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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New study monitors Real-World safety of asthma drug tezepelumab in korea
Disease control Not yet recruitingThis study observes 210 patients in South Korea who are prescribed Tezepelumab for severe asthma or chronic sinusitis with nasal polyps. Researchers will track side effects and how well the drug controls symptoms in everyday use. The goal is to confirm the drug's safety and effec…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP)
Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could a Pre-Surgery drug boost nasal polyp treatment?
Disease control Not yet recruitingThis study looks at whether taking the drug stapokibart for 4 weeks before sinus surgery helps adults with chronic nasal polyps more than surgery alone. About 48 participants will receive either the drug or a placebo before their operation and be followed for nearly a year. The g…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP)
Phase: NA • Sponsor: Beijing Tongren Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Could a simple polyp removal plus a drug replace major sinus surgery?
Disease control Not yet recruitingThis study compares two treatments for chronic sinusitis with nasal polyps: a less invasive surgery (simple polyp removal) combined with an anti-IL-5 drug (mepolizumab) versus extensive sinus surgery also with the drug. About 360 participants will be randomly assigned to one of t…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP)
Phase: PHASE4 • Sponsor: Eye & ENT Hospital of Fudan University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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New shot could shrink nasal polyps and ease breathing
Symptom relief Not yet recruitingThis study tests an experimental drug called LP-003 for people with long-term sinus inflammation and nasal polyps (growths in the nose). The goal is to see if it can shrink polyps and reduce stuffiness. About 150 adults will receive either the drug or a placebo, and their progres…
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP)
Phase: PHASE2 • Sponsor: Longbio Pharma • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Could a simple mucus test transform nasal polyp treatment?
Knowledge-focused Not yet recruitingThis study looks at whether measuring the thickness (viscosity) of nasal mucus can help doctors better understand the type of inflammation in people with chronic sinusitis and nasal polyps. Researchers will compare mucus from 60 patients having sinus surgery—some with polyps and …
Matched conditions: CHRONIC RHINOSINUSITIS WITH NASAL POLYPS (CRSWNP)
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC