CHRONIC COUGH

This early-stage study will test if a brief, breath-focused therapy called Acceptance and Commitment Therapy (ACT) is practical and safe for adults with chronic cough. Researchers will enroll 30 people to see if they can stick with the program and find it helpful. The goal is to …

This study tests two common nerve-pain drugs (low-dose morphine and pregabalin) and a virtual cough-control therapy, alone or together, in 124 adults with chronic cough that hasn't improved with standard treatments. The goal is to see which approach best reduces coughing frequenc…

This study compares different anesthesia methods to see if they can prevent chronic cough after video-assisted lung surgery. 228 lung cancer patients will be randomly assigned to different airway management strategies during surgery. Researchers will track cough severity, duratio…

This study will use a special test called high-resolution manometry with impedance to closely examine how the throat and esophagus work during swallowing in 160 adults with swallowing difficulties or suspected extraesophageal reflux. Participants will also undergo 24-hour pH moni…

This observational study will analyze samples from 160 children with asthma, protracted bacterial bronchitis, or chronic cough to find biomarkers that predict disease progression and treatment response. Participants will undergo a bronchoscopy to collect lung fluid and tissue sam…