CENTRAL NERVOUS SYSTEM DISEASES
Clinical trials for CENTRAL NERVOUS SYSTEM DISEASES explained in plain language.
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New stroke device aims to restore blood flow faster
Disease control Not yet recruitingThis study is testing two medical devices called Supernova and Neutron that are designed to remove blood clots from brain arteries during a stroke. The goal is to restore blood flow quickly to minimize brain damage and help patients recover better. Researchers will track 3,000 st…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Phase: NA • Sponsor: Gravity Medical Technology, INC • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New hope for fighting deadly brain tumors: experimental drug combo enters testing
Disease control Not yet recruitingThis study is testing whether adding a new oral drug called silevertinib to standard chemotherapy (temozolomide) helps people with a specific type of aggressive brain cancer (glioblastoma) live longer without their cancer getting worse. It will involve about 162 newly diagnosed p…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Phase: PHASE2 • Sponsor: Black Diamond Therapeutics, Inc. • Aim: Disease control
Last updated Mar 02, 2026 15:27 UTC
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Scientists search brain fluid for clues to neurological diseases
Knowledge-focused Not yet recruitingThis study aims to collect and analyze spinal fluid from 1,000 children and adults with various brain and nervous system conditions. Researchers will measure protein levels over time to identify biological markers that could help doctors better understand, diagnose, and potential…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Sponsor: Imagine Institute • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists test if a natural hormone is the hidden culprit behind head injury headaches
Knowledge-focused Not yet recruitingThis study aims to understand what causes headaches after a mild head injury. Researchers will give a hormone-like substance called pramlintide to 21 people with long-term post-traumatic headaches to see if it triggers their migraine-like pain. The goal is to learn more about the…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists test brain chemical to unlock migraine mystery
Knowledge-focused Not yet recruitingThis study aims to understand if a natural brain chemical called adrenomedullin can trigger migraine attacks. Researchers will give participants a migraine prevention drug (erenumab) first to block one pathway, then give adrenomedullin to see if it still causes a migraine. The go…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists test drug to deliberately trigger migraines
Knowledge-focused Not yet recruitingThis study aims to understand what causes migraines by testing if a hormone-like drug called pramlintide can trigger a migraine attack. Researchers will give the drug or a placebo to 21 adults with migraine without aura and watch for 12 hours to see if a migraine starts. The goal…
Matched conditions: CENTRAL NERVOUS SYSTEM DISEASES
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:55 UTC