CARDIOVASCULAR RISK

This study tests a new monthly injection called ziltivekimab in 10,000 people who recently had a heart attack. The goal is to see if it can lower the risk of having another heart attack, a stroke, or dying from heart disease. Participants will receive either the study drug or a p…

This study tests a digital health program called Corrie Lipids in about 1,000 adults with high LDL cholesterol and heart disease risk. The program includes a smartphone app for tracking cholesterol, medication reminders, and education, plus training for doctors to improve cholest…

This study looks at how different amounts of resistance exercise (like weight lifting) affect heart health in overweight, inactive adults. Participants are split into groups that do aerobic exercise alone or aerobic plus varying durations of resistance training. The goal is to de…

This study asks whether oral health—including tooth loss, chewing ability, and tongue strength—can help explain why some people develop stiff arteries, a key sign of vascular aging and heart disease risk. Researchers will assess mouth structure and function in 750 adults and comp…

This study looks at how often people with cystic fibrosis and diabetes develop complications like eye, kidney, and nerve problems. Researchers will also check blood pressure and cholesterol. The goal is to better understand these risks in a diverse group of 200 adolescents and ad…

This study is testing whether adding genetic and imaging information to standard risk assessments can better predict heart disease in 30,000 healthy Italian adults aged 40-80. Participants will have their risk calculated using traditional methods and then again with the added dat…