CARDIOVASCULAR RISK

This trial tests whether a shared decision-making tool, called CV Prevention Choice, can help primary care doctors and their patients have better conversations about preventing heart disease. The tool uses each patient's electronic health record to estimate their personal cardiov…

This Phase 3 trial is testing whether a monthly injection of ziltivekimab can reduce the risk of heart attacks and strokes in 6,200 people who already have heart disease, chronic kidney disease, and signs of inflammation. Participants receive either the drug or a placebo for up t…

This completed study tested a 9-month program using the APA-FIT app to help 520 adults with chronic conditions improve their physical activity, diet, and mental health. Participants received personalized exercise plans, nutrition guidance, and mental health support. The study com…

This study tested an experimental drug, ziltivekimab, in 36 adults with advanced chronic kidney disease (not on dialysis) to see if it can safely reduce inflammation and related heart risks. Participants received either a low dose, a high dose, or a placebo injection every 4 week…

This completed study tested whether canagliflozin, a diabetes drug, can reduce scarring in the heart muscle of people with type 2 diabetes who are at high risk for heart problems. 45 participants were randomly assigned to take either canagliflozin or sitagliptin daily. Researcher…

This study is testing whether an artificial intelligence software called CLAiR can reliably identify people at elevated risk for heart disease by analyzing images of the back of the eye (retina). The software looks for patterns in retinal images that may correlate with cardiovasc…

This study tested a digital health program that combines online tools and phone coaching to help adults adopt healthier habits and prevent heart disease. Over 2,600 participants used the program for at least one year. Researchers measured changes in cardiovascular risk, physical …

This completed study offered free heart health checks to 1366 healthcare professionals attending the ESC Congress 2025. Participants filled out questionnaires, had blood drawn, and received blood pressure and heart sound checks. The goal was to assess cardiovascular risk and info…