CANNABIS USE DISORDER, SEVERE
Clinical trials for CANNABIS USE DISORDER, SEVERE explained in plain language.
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Can a common nerve pain drug restore brain chemistry in bipolar cannabis users?
Disease control CompletedThis study tests whether gabapentin, an FDA-approved medication, can help restore the balance of key brain chemicals (GABA and glutamate) in people with bipolar disorder who also use cannabis. Participants are randomly assigned to receive either gabapentin or a placebo for 17 day…
Matched conditions: CANNABIS USE DISORDER, SEVERE
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Can quitting cannabis rewire the Brain's threat and reward responses?
Knowledge-focused CompletedThis study investigates how three weeks of cannabis abstinence influences brain responses to threat, reward, and cannabis cues in women with cannabis use disorder. Participants are randomly assigned to either continue using cannabis as usual or abstain for three weeks, with lab v…
Matched conditions: CANNABIS USE DISORDER, SEVERE
Phase: NA • Sponsor: Florida State University • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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Hormones may hold key to cannabis addiction recovery
Knowledge-focused CompletedThis study looked at how sex hormones and gender influence recovery from cannabis use disorder. 224 adults who wanted to cut down on cannabis received 8 weeks of counseling, including one-on-one goal setting and computerized therapy. They also provided daily saliva samples to tra…
Matched conditions: CANNABIS USE DISORDER, SEVERE
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC