CADASIL
Clinical trials for CADASIL explained in plain language.
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Natural compound tested to fight rare brain disease
Disease control CompletedThis study tested whether a natural vitamin E compound called palm tocotrienols (HOV-12020) could slow down the progression of CADASIL, a rare inherited brain disease that causes strokes and cognitive decline. Fifty patients with confirmed CADASIL took either the study drug or a …
Matched conditions: CADASIL
Phase: PHASE2 • Sponsor: Hovid Berhad • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Gene test cuts diagnosis time for devastating childhood brain diseases from years to months
Diagnosis CompletedThis study tested whether using whole genome sequencing (a complete genetic map) as a first test could diagnose children with rare, inherited brain disorders called leukodystrophies faster and more accurately than the standard step-by-step approach. Researchers enrolled 236 child…
Matched conditions: CADASIL
Sponsor: Children's Hospital of Philadelphia • Aim: Diagnosis
Last updated Mar 25, 2026 14:07 UTC
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Scientists map Brain's blood flow in rare genetic disorder
Knowledge-focused CompletedThis study aimed to better understand CADASIL, a rare genetic condition that affects blood vessels in the brain. Researchers used MRI and EEG brain scans on 60 participants to see how blood flow and brain cell activity are connected in people with this disease. The goal was to ga…
Matched conditions: CADASIL
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC