CADASIL
Clinical trials for CADASIL explained in plain language.
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Could a palm extract help fight a rare genetic brain disease?
Disease control CompletedThis study tested a supplement called HOV-12020 (made from palm tocotrienols) in 50 adults aged 45-75 with CADASIL, a rare genetic disease that damages small blood vessels in the brain, leading to strokes and memory loss. The goal was to see if the supplement could reduce worseni…
Matched conditions: CADASIL
Phase: PHASE2 • Sponsor: Hovid Berhad • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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NIH launches study to unravel mysteries of rare genetic brain disease CADASIL
Knowledge-focused CompletedThis study looked at 20 people with CADASIL, a rare genetic disease that damages brain arteries and causes migraines, strokes, and dementia. Researchers used blood tests, skin biopsies, eye exams, and brain scans to learn more about how the disease works. The goal was to better u…
Matched conditions: CADASIL
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Brain scans reveal hidden clues in rare stroke disorder
Knowledge-focused CompletedThis study looked at how blood flow and brain activity are linked in people with CADASIL, a rare genetic disease that causes small strokes. Researchers used MRI and EEG scans to measure these connections in 60 adults. The goal was to better understand the disease, not to test a n…
Matched conditions: CADASIL
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Could a single DNA test solve the mystery of rare brain diseases in kids?
Knowledge-focused CompletedThis study looked at whether whole genome sequencing (a complete read of a person's DNA) can help diagnose leukodystrophies, a group of rare brain diseases that are hard to identify. Researchers enrolled 236 children with white matter abnormalities on brain scans but no known gen…
Matched conditions: CADASIL
Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC