CADASIL

This study collects medical information and biological samples (like blood or tissue) from up to 12,000 people with leukodystrophies—rare disorders that damage the brain's white matter. Researchers will use this data to find new genetic causes, develop biomarkers for future trial…

This study follows 660 adults with or at risk for CADASIL, a genetic condition that damages small blood vessels in the brain and can lead to dementia. Over 5 years, researchers will use memory tests, brain scans, and blood tests to track how the disease progresses. The goal is to…

This study follows 500 Korean adults with CADASIL, a genetic condition that causes strokes and dementia, for up to 10 years. Researchers will track symptoms, brain scans, and memory tests to learn how the disease progresses in this population. The goal is to find better ways to c…

This study is creating a large network of hospitals across Italy to improve the diagnosis and understanding of rare cerebrovascular diseases (rCVDs), such as CADASIL, Fabry disease, and Moyamoya. Researchers will collect medical information and blood samples from 500 patients to …

This study enrolls 500 people with signs of cerebral small vessel disease (CSVD) to see how genetics and MRI brain changes affect future stroke and dementia risk. Participants provide a blood sample for genetic testing and undergo brain scans, then are followed for at least 2 yea…