BRONCHIOLITIS OBLITERANS SYNDROME
Clinical trials for BRONCHIOLITIS OBLITERANS SYNDROME explained in plain language.
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New drug may help lung damage after stem cell transplants
Disease control OngoingThis study tests a new oral drug called alvelestat (MPH966) in adults who have lung damage (bronchiolitis obliterans syndrome) after a stem cell transplant. The drug aims to block an enzyme that may cause lung injury. The trial has two parts: first to find the safest and most eff…
Matched conditions: BRONCHIOLITIS OBLITERANS SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Could a cancer drug help lung damage after transplant?
Disease control OngoingThis phase 2 study tests the drug ruxolitinib (Jakafi) in 50 people who developed bronchiolitis obliterans syndrome (BOS) after a stem cell transplant. BOS is a serious lung condition that causes scarring and breathing problems. The goal is to see if ruxolitinib can improve lung …
Matched conditions: BRONCHIOLITIS OBLITERANS SYNDROME
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Can a simple home breathing test catch lung trouble early in transplant patients?
Knowledge-focused OngoingThis study follows 250 people who have had a donor stem cell transplant to see if respiratory viruses lead to a lung condition called bronchiolitis obliterans syndrome (BOS). Participants use a handheld device at home to measure lung function and provide nasal swabs and blood sam…
Matched conditions: BRONCHIOLITIS OBLITERANS SYNDROME
Sponsor: Fred Hutchinson Cancer Center • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC