BREAST NEOPLASM FEMALE

This study looks at whether adding a CDK4/6 inhibitor (a targeted drug) to hormone therapy earlier or later works better for women with advanced hormone-receptor-positive breast cancer. About 1,050 women will receive either the drug combo first followed by another hormone therapy…

This study tests a combination of three drugs (nivolumab, bicalutamide, and ipilimumab) in 30 people with advanced HER2-negative breast cancer that has spread. The goal is to see if this chemo-free approach can control the disease for at least 24 weeks. Participants must have mea…

This study is testing whether a simple breath test can tell if a woman has breast cancer. Researchers are collecting breath samples from 1000 women — half with breast cancer and half without — and analyzing them with a mass spectrometer. The goal is to see if the chemical signatu…

This phase 3 trial tests a long-acting injection called PEG-G-CSF to prevent severe neutropenia (dangerously low white blood cell counts) after chemotherapy in 250 women with breast cancer. Participants receive either the test drug or the already-approved Neulasta. The goal is to…

This study tests whether a 12-week online yoga program can reduce fatigue and inflammation in women who have had breast cancer surgery. 229 participants are randomly assigned to either the yoga group or standard care. The goal is to see if yoga helps with energy, stress, and dail…

This study is testing a new lab test called the RNA Disruption Assay (RDA) to see if it can tell how well breast cancer is responding to chemotherapy. Researchers will take small tissue samples (biopsies) from the tumor at specific times during treatment and analyze them. The goa…