BREAST DISEASES
Clinical trials for BREAST DISEASES explained in plain language.
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New drug targets rare cancer mutation in early trial
Disease control OngoingThis early-phase study tests a new oral drug, ATV-1601, in people with advanced solid tumors or certain breast cancers that have a specific AKT1 E17K mutation. The main goals are to check safety, find the right dose, and see how the drug moves through the body. About 134 adults w…
Matched conditions: BREAST DISEASES
Phase: PHASE1 • Sponsor: Atavistik Bio, Inc • Aim: Disease control
Last updated Aug 09, 2026 00:00 UTC
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Can a Four-Drug cocktail tame a tough breast cancer?
Disease control OngoingThis trial is testing whether combining four drugs—anastrozole, palbociclib, trastuzumab, and pertuzumab—can safely and effectively treat HR-positive, HER2-positive metastatic breast cancer as a first-line therapy. The study involves people who have not received prior systemic tr…
Matched conditions: BREAST DISEASES
Phase: PHASE1, PHASE2 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Could a safer, No-Needle MRI replace Dye-Based breast scans?
Diagnosis OngoingThis study is testing whether a special MRI that does not require a contrast dye injection can accurately detect breast cancer or other breast diseases. Over 1,000 women at risk or with suspected breast issues will receive the new MRI alongside standard care. The goal is to see i…
Matched conditions: BREAST DISEASES
Sponsor: Perspectum • Aim: Diagnosis
Last updated Jun 27, 2026 12:36 UTC
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Could a quick MRI catch more breast cancers in black women?
Diagnosis OngoingThis study is testing whether a fast breast MRI can find cancers that mammograms miss in Black women with dense breast tissue. About 500 African American women who recently had a normal mammogram will get an additional abbreviated MRI. Researchers want to see if this extra scan d…
Matched conditions: BREAST DISEASES
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC