BRAIN TUMOR, RECURRENT
Clinical trials for BRAIN TUMOR, RECURRENT explained in plain language.
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Brain tumor trial delivers targeted toxin directly into tumors
Disease control CompletedThis phase 1 study tested a drug called D2C7-IT in 81 adults with recurrent malignant glioma (a type of brain tumor). The drug is a lab-made antibody linked to a toxin that targets specific proteins on tumor cells. It was infused directly into the tumor over 72 hours using thin t…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE1 • Sponsor: Darell Bigner • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Sound waves + radiation: new hope for tough brain tumors?
Disease control CompletedThis small pilot study tested whether combining focused ultrasound with a second round of radiation is safe for people with recurrent glioblastoma, an aggressive brain cancer. Seven adults who had already tried standard treatments received the combination therapy. The goal was to…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: NA • Sponsor: NaviFUS Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Glow-in-the-Dark dye could help surgeons spot hidden brain tumors
Disease control CompletedThis completed Phase 1 trial tested whether a dye called indocyanine green (ICG) can make brain tumor cells glow during surgery, helping surgeons see and remove them more completely. 363 adults with brain tumors received an ICG injection before surgery, and special cameras captur…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE1 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New contrast agent shows promise for brain tumor MRI scans
Diagnosis CompletedThis completed Phase 3 trial tested whether Elucirem (gadopiclenol) provides better MRI images of brain gliomas compared to the standard contrast agent Dotarem. 138 adults with primary or recurrent brain tumors received one of the two agents during DSC-MRI perfusion scans. The ma…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE3 • Sponsor: Guerbet • Aim: Diagnosis
Last updated Jun 27, 2026 09:00 UTC
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New Gadolinium-Free MRI dye shows promise for brain scans
Diagnosis CompletedThis study tested a new MRI contrast agent called RVP-001, made with manganese instead of gadolinium, in 18 adults with known brain lesions (like tumors or multiple sclerosis). The goal was to see if it is safe and can detect lesions as well as current gadolinium-based dyes. Each…
Matched conditions: BRAIN TUMOR, RECURRENT
Phase: PHASE2 • Sponsor: Reveal Pharmaceuticals Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 08:06 UTC