BLINDNESS

This study tests whether injecting a person's own bone marrow stem cells into or near the eye can help treat various retinal and optic nerve diseases, including age-related macular degeneration, retinitis pigmentosa, and glaucoma. Participants receive stem cell injections via dif…

This phase 3 trial tests an experimental drug called sepofarsen in 32 people with Leber congenital amaurosis (LCA), a rare genetic condition that causes severe vision loss from birth. The drug is injected into one eye, while the other eye gets a placebo, to see if it safely impro…

This early-stage trial is testing a brain implant designed to create artificial vision in people who are blind. Five participants will have a wireless device surgically placed in the part of the brain that processes vision. The study will check if the device is safe and whether i…

This pilot study is testing a brain implant that uses tiny electrodes to stimulate the visual cortex, aiming to create simple visual perceptions (phosphenes) in blind individuals. Five participants will undergo a small skull opening to receive the implant. The goal is to see if t…

This study looks at how blind people use a white cane to sense the world around them, not just to move. Researchers will test how well users can feel where a touch happens on the cane and measure brain activity during these tasks. The goal is to understand how the cane becomes an…