BILIARY TRACT NEOPLASMS
Clinical trials for BILIARY TRACT NEOPLASMS explained in plain language.
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Immune cells take on rare bile duct cancer in early trial
Disease control OngoingThis early-phase trial tests whether a patient's own immune cells, called tumor-infiltrating lymphocytes (TIL), can shrink advanced bile duct cancers. Four participants receive chemotherapy to prepare their immune system, then an infusion of their own TIL cells plus high-dose ald…
Matched conditions: BILIARY TRACT NEOPLASMS
Phase: PHASE2 • Sponsor: Udai Kammula • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New pill targets hard-to-treat cancers with KRAS mutation
Disease control OngoingThis study tests an experimental drug called LY3537982 in people with advanced solid tumors that have a specific KRAS G12C mutation. The goal is to see if the drug is safe and shrinks tumors. About 540 participants with lung, colorectal, endometrial, ovarian, pancreatic, or bile …
Matched conditions: BILIARY TRACT NEOPLASMS
Phase: PHASE1, PHASE2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Immunotherapy combo shows promise in bile duct cancer trial
Disease control OngoingThis phase 3 trial tests whether adding the immunotherapy drug durvalumab to standard chemotherapy (gemcitabine plus cisplatin) helps people with advanced biliary tract cancer live longer. About 810 participants received either durvalumab or a placebo alongside chemo. The study m…
Matched conditions: BILIARY TRACT NEOPLASMS
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New drug combo shows promise for Hard-to-Treat HER2 cancers
Disease control OngoingThis study tests a two-drug combination (tucatinib and trastuzumab) in people with advanced solid tumors that have HER2 alterations. The goal is to see if the treatment can shrink or control tumors. About 217 participants with various cancers (like lung, uterine, or bile duct) wi…
Matched conditions: BILIARY TRACT NEOPLASMS
Phase: PHASE2 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New study compares two drainage techniques to ease jaundice in advanced cancer patients
Symptom relief TerminatedThis study compares two minimally invasive procedures to drain blocked bile ducts in patients with incurable cancer. One method drains the bile duct into the intestine, the other drains the gallbladder into the stomach. The goal is to see which approach causes fewer complications…
Matched conditions: BILIARY TRACT NEOPLASMS
Phase: NA • Sponsor: Hospital Universitari de Bellvitge • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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New study tests safer bile duct drainage for cancer patients
Symptom relief TerminatedThis study compares two procedures to relieve bile duct blockage caused by cancer. About 120 patients with pancreatic or bile duct cancer will be randomly assigned to get either a newer ultrasound-guided drainage or the standard ERCP procedure. The goal is to see which method has…
Matched conditions: BILIARY TRACT NEOPLASMS
Phase: NA • Sponsor: Hospital Universitari de Bellvitge • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC