B CELL MALIGNANCIES
Clinical trials for B CELL MALIGNANCIES explained in plain language.
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MRNA cancer therapy enters human testing for tough blood cancers
Disease control Not yet recruitingThis early-phase trial tests a new mRNA drug (WGb-0301) for people with B-cell blood cancers that have come back or not responded to standard treatments. The drug uses lipid nanoparticles to deliver mRNA that targets CD19 on cancer cells, aiming to clear them safely. Only 9 parti…
Matched conditions: B CELL MALIGNANCIES
Phase: EARLY_PHASE1 • Sponsor: Sichuan University • Aim: Disease control
Last updated May 17, 2026 04:17 UTC
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New CAR T-Cell therapy targets Hard-to-Treat blood cancers
Disease control Not yet recruitingThis study tests a new treatment called SHB-02-CD19 for people with certain blood cancers (B-cell malignancies) that have come back or not responded to standard therapy. The treatment uses the patient's own immune cells, modified to recognize and attack cancer cells. The goal is …
Matched conditions: B CELL MALIGNANCIES
Phase: PHASE1, PHASE2 • Sponsor: Sheba Medical Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Double-Pronged CAR t cells take on tough blood cancers
Disease control Not yet recruitingThis early-phase trial tests a new type of CAR T cell therapy that targets two proteins (CD19 and CD20) on cancer cells. It is for adults with B-cell leukemia or lymphoma who have run out of standard treatments, including commercial CAR T cells. The main goal is to check safety a…
Matched conditions: B CELL MALIGNANCIES
Phase: PHASE1 • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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New study aims to unlock immune secrets in blood cancers
Knowledge-focused Not yet recruitingThis study looks at two immune receptors, CD85d and CD305, in people with B-cell blood cancers. Researchers want to see how these receptors are expressed in different cancer types and if they can help predict how the disease will progress. The goal is to better understand these c…
Matched conditions: B CELL MALIGNANCIES
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC
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Scientists probe hidden markers in blood cancers
Knowledge-focused Not yet recruitingThis study aims to understand how two specific proteins, CD274 and CD276, are present in different types of B-cell cancers. Researchers will analyze blood and bone marrow samples from 159 newly diagnosed patients using a lab technique called flow cytometry. The goal is to gather …
Matched conditions: B CELL MALIGNANCIES
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Apr 15, 2026 16:16 UTC