AUTOIMMUNE HEPATITIS

This early study tests whether siplizumab can safely prevent the immune system from attacking a new liver in people with autoimmune hepatitis or primary sclerosing cholangitis. Eight participants will receive two doses of the drug around the time of transplant and be monitored fo…

This study tests whether adding belimumab (a drug approved for lupus) to standard therapy can better control autoimmune hepatitis, a chronic liver disease. About 48 adults with active or stable disease will receive weekly injections for 72 weeks. The goal is to reduce liver infla…

This study tests whether eating a Mediterranean diet reduces fatigue in people with autoimmune hepatitis better than a Western diet. About 48 adults will try both diets in a random order. The goal is to see if changing what you eat can improve quality of life.

This study looks at gut bacteria in 3,000 adults with chronic liver diseases like autoimmune hepatitis and fatty liver. Researchers want to find which bacteria are linked to each disease and how they affect disease progression. Participants provide stool samples for analysis, but…

This study is creating a new tool to help doctors diagnose and choose treatments for autoimmune diseases. Researchers will analyze blood samples from 500 children with autoimmune conditions and healthy children to find patterns in genes and other molecules. The goal is to make di…