AUTOIMMUNE ENCEPHALITIS (AE)
Clinical trials for AUTOIMMUNE ENCEPHALITIS (AE) explained in plain language.
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Could a new Antibody-Lowering drug ease autoimmune brain inflammation?
Disease control Not yet recruitingThis Phase 2 trial tests efgartigimod PH20 SC, a drug that lowers harmful antibodies, in 170 adults and teens with autoimmune encephalitis (AIE). Participants receive either the drug or a placebo, and researchers measure changes in disability and symptoms over up to 3 years. The …
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Phase: PHASE2 • Sponsor: argenx • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Could fewer plasma exchange sessions be just as effective for kids with brain inflammation?
Disease control Not yet recruitingThis trial tests whether plasma exchange (a blood-cleaning procedure) given every other day works as well as daily sessions for children with autoimmune encephalitis, a condition where the immune system attacks the brain. The study involves 22 children who are randomly assigned t…
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Phase: NA • Sponsor: Menoufia University • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Cancer drug repurposed to calm brain inflammation in autoimmune disease
Disease control Not yet recruitingThis study tests whether a low dose of blinatumomab, a drug originally used for leukemia, can help people with severe autoimmune encephalitis or cerebellitis that hasn't responded to standard treatments. The drug targets and depletes certain immune cells (B cells) that are mistak…
Matched conditions: AUTOIMMUNE ENCEPHALITIS (AE)
Phase: PHASE4 • Sponsor: Beijing Tiantan Hospital • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC