ARTHRITIS KNEE
Clinical trials for ARTHRITIS KNEE explained in plain language.
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Knee surgery pain relief: could a simple injection replace opioids?
Symptom relief CompletedThis study tested whether injecting a mix of painkillers (bupivacaine, ketorolac, and epinephrine) around the knee during total knee replacement surgery could reduce pain and improve function better than standard pain medicines alone. Eighty adults with end-stage knee arthritis t…
Matched conditions: ARTHRITIS KNEE
Phase: NA • Sponsor: Damascus University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New study aims to make sedation safer for obese joint surgery patients
Symptom relief CompletedThis study looked at 110 obese patients (BMI over 25) having knee or hip replacement surgery under spinal anesthesia. Researchers compared two ways to calculate the dose of the sedative remimazolam: using ideal body weight versus total body weight. The goal was to find which dose…
Matched conditions: ARTHRITIS KNEE
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Weight-Loss surgery before knee replacement: does it help or hurt?
Knowledge-focused CompletedThis study examined nearly 100,000 people who had knee replacement for arthritis to see if those who previously had weight-loss surgery faced different risks of complications or needing another surgery. Researchers focused on how body weight at the time of knee replacement and th…
Matched conditions: ARTHRITIS KNEE
Sponsor: Bispebjerg Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Knee cement checked: simplex HV holds up over two years
Knowledge-focused CompletedThis study looked back at 200 patients who had a knee replacement using Simplex HV bone cement. The goal was to see if the cement kept the implant in place without needing a second surgery within two years. Researchers also measured knee motion and function using the Knee Society…
Matched conditions: ARTHRITIS KNEE
Sponsor: Stryker Orthopaedics • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC