ARTERIOVENOUS FISTULA

This study tests a new device that creates dialysis access through a small skin puncture instead of open surgery. It involves 126 adults with kidney failure who need dialysis. The goal is to see if the procedure is safe and works well, with participants followed for up to five ye…

This study is testing a medical device called the Cera Vascular Plug, which is used to block blood flow in blood vessels. It is for people with conditions like aneurysms, abnormal connections between arteries and veins, or bleeding in the spleen. The goal is to confirm the device…

This study tests a special wrap called SelfWrap placed around blood vessels during fistula creation for dialysis. The goal is to help the fistula mature faster and work without extra procedures. About 600 adults with chronic kidney disease needing a new fistula will take part. Th…

This study tests whether a short course of the blood thinner apixaban can help arteriovenous fistulas mature properly in people with end-stage kidney disease. About 190 adults will receive either apixaban or a placebo around the time of fistula creation surgery. The goal is to se…

This study is testing a device called the BD WavelinQ EndoAVF System, which creates a connection between an artery and a vein (called an AV fistula) in people with kidney failure who need dialysis. The goal is to see if this device helps make dialysis treatments more successful a…

This study tests a new liquid material that blocks abnormal blood vessels in the brain. About 116 adults with brain arteriovenous malformation (AVM) will receive this treatment or a standard one. The goal is to see if the new liquid is as safe and effective at reducing the size o…

This study tests a new way to do dialysis using only one needle in the arm's blood vessel and a second needle in the leg to return cleaned blood. The goal is to reduce damage to the main dialysis blood vessel, lower the risk of complications like scarring and blockages, and cut d…