APATHY

This study tested a 12-week supervised diet and exercise program for older adults with insulin resistance and apathy, a lack of motivation. Researchers wanted to see if the program improved these conditions and whether adding soybeans to the diet made it more effective. Participa…

This study tested whether magnetic stimulation applied to the front of the brain could improve apathy—a severe loss of motivation—in older Veterans with mild memory problems. Participants received either real or fake stimulation over 20 sessions to see if it could restore motivat…

This early-stage study tested how a new drug called IRL757 moves through and is processed by the body. Twelve healthy volunteers aged 65 and older received a single oral dose to measure drug levels in their blood and urine over time. The main goal was to understand the drug's saf…

This study aimed to understand how apathy affects different types of fatigue in older adults with mild memory problems. Researchers compared 57 participants with and without apathy, measuring their activity levels, fatigue, and movement patterns. The study involved wearing activi…

This small pilot study tested whether wearable sensors could measure apathy (loss of motivation) in people with frontotemporal dementia during everyday activities. Researchers compared 14 participants—some with dementia and some healthy—to see if sensors could detect patterns of …