ANTIBIOTIC PROPHYLAXIS
Clinical trials for ANTIBIOTIC PROPHYLAXIS explained in plain language.
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Can a mushroom extract cut sinus infections and antibiotic use?
Disease control CompletedThis study tested whether adding a supplement called Imunoglukan P4H® (made from pleuran, a mushroom extract) to standard care (nasal sprays and rinses) could reduce sinus flare-ups, respiratory infections, and the need for antibiotics in people over 12 with newly diagnosed chron…
Matched conditions: ANTIBIOTIC PROPHYLAXIS
Phase: NA • Sponsor: Pleuran, s.r.o. • Aim: Disease control
Last updated May 17, 2026 11:35 UTC
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Knee surgery infection prevention: one dose may be enough
Disease control CompletedThis study looked at the best way to give antibiotics before and after knee replacement surgery to prevent joint infections. About 1,770 adults having elective knee replacement took part. Researchers compared a single dose before surgery versus a longer 24-hour course to see whic…
Matched conditions: ANTIBIOTIC PROPHYLAXIS
Phase: PHASE4 • Sponsor: Duke University • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Tailored antibiotics cut infection risk after pancreatic surgery
Disease control CompletedThis study looked at 117 adults having pancreatic surgery who had a bile duct stent placed beforehand. Researchers compared infection rates when using a newer antibiotic (piperacillin/tazobactam) versus older ones (cephalosporins). The goal was to see if matching antibiotics to l…
Matched conditions: ANTIBIOTIC PROPHYLAXIS
Sponsor: Central Hospital, Nancy, France • Aim: Disease control
Last updated May 13, 2026 15:59 UTC