ANCA ASSOCIATED VASCULITIS (AAV)
Clinical trials for ANCA ASSOCIATED VASCULITIS (AAV) explained in plain language.
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New drug combo may spare kidneys in rare autoimmune disease
Disease control Not yet recruitingThis study tests whether adding avacopan to standard treatment helps people with severe ANCA vasculitis and kidney damage. About 130 adults with newly diagnosed or relapsing disease will receive either avacopan or a placebo alongside usual therapy. The goal is to see if more pati…
Matched conditions: ANCA ASSOCIATED VASCULITIS (AAV)
Phase: PHASE3 • Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Can early treatment stop vasculitis relapses? new trial aims to find out
Disease control Not yet recruitingThis study looks at whether giving the drug rituximab early, when a blood marker (ANCA) reappears, can prevent disease flare-ups in people with two types of vasculitis (GPA and MPA). About 70 adults who have been on maintenance rituximab for at least 18 months will be randomly as…
Matched conditions: ANCA ASSOCIATED VASCULITIS (AAV)
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New cell therapy trial offers hope for kids with tough autoimmune diseases
Disease control Not yet recruitingThis early-stage study will test a new cell therapy called YTS109 in 12 children aged 5 to 17 with severe autoimmune diseases like lupus and scleroderma that haven't responded to other treatments. The goal is to see if the therapy is safe and can help control the disease. Childre…
Matched conditions: ANCA ASSOCIATED VASCULITIS (AAV)
Phase: PHASE1 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated May 01, 2026 15:57 UTC