ANCA-ASSOCIATED VASCULITIS (AAV)
Clinical trials for ANCA-ASSOCIATED VASCULITIS (AAV) explained in plain language.
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Can early rituximab stop vasculitis relapses? new study aims to find out
Disease control Not yet recruitingThis study looks at whether giving the drug rituximab early, when signs of the disease reappear in the blood, can prevent relapses in people with certain types of vasculitis (GPA and MPA). About 70 adults who have been on maintenance rituximab for at least 18 months will be rando…
Matched conditions: ANCA-ASSOCIATED VASCULITIS (AAV)
Phase: PHASE4 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Experimental cell infusion aims to tame childhood autoimmune diseases
Disease control Not yet recruitingThis early-stage trial will test a new cell therapy called YTS109 in 12 children aged 5 to 17 with severe autoimmune diseases like lupus or scleroderma that have not responded to standard treatments. The children will receive a single infusion of these cells, and researchers will…
Matched conditions: ANCA-ASSOCIATED VASCULITIS (AAV)
Phase: PHASE1 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New drug combo aims to save kidneys in rare autoimmune disease
Disease control Not yet recruitingThis Phase 3 trial tests whether adding avacopan to standard treatment helps people with severe ANCA vasculitis and serious kidney damage. About 130 participants will receive either avacopan or a placebo alongside usual care. The goal is to see if more patients recover kidney fun…
Matched conditions: ANCA-ASSOCIATED VASCULITIS (AAV)
Phase: PHASE3 • Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC