New drug combo may spare kidneys in rare autoimmune disease

NCT ID NCT07373262

First seen Jan 30, 2026 · Last updated May 13, 2026 · Updated 15 times

Summary

This study tests whether adding avacopan to standard treatment helps people with severe ANCA vasculitis and kidney damage. About 130 adults with newly diagnosed or relapsing disease will receive either avacopan or a placebo alongside usual therapy. The goal is to see if more patients recover kidney function by one year without serious side effects or needing extra treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANCA ASSOCIATED VASCULITIS (AAV) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amiens Hospital

    Amiens, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Angers Hospital

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Besançon Hospital

    Besançon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bichat Hospital

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bordeaux Hospital

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Boulogne-sur-Mer Hospital

    Boulogne-sur-Mer, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Brest Hospital

    Brest, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Caen Hospital

    Caen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cochin Hospital

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • George Pompidou Hospital

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Grenoble Hospital

    Grenoble, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Henri Mondor Hospital

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kremlin Bicêtre Hospital

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Le Mans Hospital

    Le Mans, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lille Hospital

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Limoges Hospital

    Limoges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Marseille Hospital

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NANCY Hospital

    Vandœuvre-lès-Nancy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nantes Hospital

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Necker Hospital

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nimes Hospital

    Nîmes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ROuen Hospital

    Rouen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Reims Hospital

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint exupery hospital

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Strasbourg Hospital

    Strasbourg, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tenon Hospital

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Toulouse Hospital

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tours Hospital

    Tours, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Valenciennes Hospital

    Valenciennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vendée Hospital

    La Roche-sur-Yon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.