AML (ACUTE MYELOID LEUKEMIA)
Clinical trials for AML (ACUTE MYELOID LEUKEMIA) explained in plain language.
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Gentler treatment tested for frail leukemia patients
Disease control Not yet recruitingThis study is testing a new treatment plan for adults with a type of blood cancer called acute myeloid leukemia (AML) who are too old or frail for standard strong chemotherapy. The plan uses a drug called selinexor, aiming to reduce or avoid traditional chemotherapy drugs to see …
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: NA • Sponsor: Donghua Zhang • Aim: Disease control
Last updated Apr 01, 2026 23:26 UTC
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New hope for blood cancer patients: trial tests gentler treatment against harsh chemo
Disease control Not yet recruitingThis trial is testing whether a new combination of three targeted drugs works better than the standard, more intensive chemotherapy for adults newly diagnosed with a specific genetic type of acute myeloid leukemia (AML). The study will involve about 230 patients who are healthy e…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: PHASE2, PHASE3 • Sponsor: European Organisation for Research and Treatment of Cancer - EORTC • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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New 'Living Drug' trial targets tough blood cancers
Disease control Not yet recruitingThis is a first-in-human study testing a new type of CAR T-cell therapy for adults with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) that has come back or not responded to other treatments. Doctors will collect a patient's own immune cells, genetically…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: PHASE1 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Scientists test gentler prep for blood cancer transplants
Disease control Not yet recruitingThis study is testing the safety of adding a drug called venetoclax to a standard, lower-intensity chemotherapy regimen given before a stem cell transplant. The goal is to see if this combination can better control acute myeloid leukemia (AML) or high-risk myelodysplastic syndrom…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: PHASE2 • Sponsor: University Hospital Tuebingen • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Double-Punch therapy trial aims to tame aggressive blood cancer
Disease control Not yet recruitingThis study is testing a new two-step treatment for adults with acute myeloid leukemia (AML) that has returned or not responded to standard chemotherapy. First, patients receive an immune cell therapy (CLL1 CAR-T) designed to target their cancer cells. This is followed by a stem c…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: NA • Sponsor: Donghua Zhang • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Double-Punch CAR-T trial aims to tame tough leukemia
Disease control Not yet recruitingThis early-phase study is testing a new two-step treatment for adults with acute myeloid leukemia (AML) that has come back or hasn't responded to other therapies. Doctors will first give patients one type of engineered immune cell (CAR-T), then a second type, with the goal of con…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: EARLY_PHASE1 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for kids with leukemia: early trial tests cutting-edge CAR-T treatment
Disease control Not yet recruitingThis is an early-stage study to test the safety and see if a new type of CAR-T cell therapy might help children whose acute myeloid leukemia has come back or hasn't responded to other treatments. Doctors will collect a child's own immune cells, modify them in a lab to target a pr…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: EARLY_PHASE1 • Sponsor: First Affiliated Hospital of Guangxi Medical University • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New transplant prep could boost survival for blood cancer patients
Disease control Not yet recruitingThis study aims to find out which of two chemotherapy drugs works better to prepare patients for a stem cell transplant for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). It will compare treosulfan and melphalan in 220 adult patients who are at higher risk for si…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: PHASE2 • Sponsor: Technische Universität Dresden • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New 'Living Drug' trial offers hope for Tough-to-Treat blood cancer
Disease control Not yet recruitingThis study is testing a new, experimental treatment for adults whose acute myeloid leukemia (AML) has come back or hasn't responded to standard therapies. Doctors will collect a patient's own immune cells, modify them in a lab to better target the cancer, and then infuse them bac…
Matched conditions: AML (ACUTE MYELOID LEUKEMIA)
Phase: PHASE1, PHASE2 • Sponsor: Xuzhou Medical University • Aim: Disease control
Last updated Feb 27, 2026 15:19 UTC