New combo aims to outdo standard chemo for FLT3-Mutated leukemia

NCT ID NCT07425808

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new three-drug combination (gilteritinib, azacitidine, and venetoclax) against standard chemotherapy for adults with a specific genetic subtype of acute myeloid leukemia (FLT3-ITD). About 230 newly diagnosed patients aged 18-75 who are healthy enough for intensive chemo will be randomly assigned to one of the two treatments. The goal is to see if the new combo leads to better survival and remission rates.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia acute myeloid leukemia, FLT3 internal tandem duplication

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••