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Clinical trials for AMD explained in plain language.
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New pill aims to slow blinding eye disease
Disease control CompletedThis study tested whether a daily capsule called ALK-001 could slow the progression of geographic atrophy, a severe form of age-related macular degeneration that causes permanent vision loss. About 300 people with this condition were randomly assigned to receive either the study …
Matched conditions: AMD
Phase: PHASE2, PHASE3 • Sponsor: Alkeus Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Researchers dig into old eye scans to predict blindness risk
Knowledge-focused CompletedThis study looked back at existing medical records and eye scans from 60 patients with geographic atrophy, a severe form of dry macular degeneration that causes vision loss. The goal was to understand which specific features of the retina seen on scans are linked to faster vision…
Matched conditions: AMD
Sponsor: IRCCS Ospedale San Raffaele • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists probe Eye's inner shield in Vision-Loss fight
Knowledge-focused CompletedThis study aimed to understand how two common eye injections for wet age-related macular degeneration (AMD) affect a protective barrier inside the eye. Researchers measured protein levels in the eye fluid of 30 patients receiving either aflibercept or brolucizumab injections. The…
Matched conditions: AMD
Phase: NA • Sponsor: The Filatov Institute of Eye Diseases and Tissue Therapy • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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New eye scan could sharpen fight against blinding disease
Knowledge-focused CompletedThis study tested a new, non-invasive eye scan called OCT angiography to see if it could better monitor patients with wet age-related macular degeneration (AMD) who were receiving standard treatment. Researchers enrolled 49 patients to see if this scan could detect subtle changes…
Matched conditions: AMD
Sponsor: Centre Hospitalier Intercommunal Creteil • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC