ALZHEIMER DEMENTIA

This study tests whether a natural brain hormone called allopregnanolone can safely slow or reverse memory loss in people with early-stage Alzheimer's. About 100 adults aged 55-80 will receive either the drug or a placebo for several months. The main goal is to see if the drug ca…

This study tests whether a blood test (Quest AD-Detect) can help doctors identify Alzheimer's disease earlier in patients hospitalized with confusion or delirium. Researchers will follow up with participants six months later to discuss results and arrange further care if needed. …

This study tests if levetiracetam, a seizure medication, can prevent epileptic seizures in 120 adults over 40 with Down syndrome and Alzheimer's disease. Participants will receive either the drug or a placebo for 96 weeks. The goal is to see if the drug can stop seizures and poss…

This early study is testing whether a natural supplement called fisetin is safe for older adults with mild Alzheimer's disease or mild cognitive impairment. Only 5 participants will take the supplement, and researchers will closely watch for any side effects. This is a very small…

This early-stage study tests whether a drug called CpG 1018, which stimulates the body's natural immune system, is safe for people with mild cognitive impairment or mild Alzheimer's dementia. About 39 participants will receive one of three doses or a placebo over 8 weeks. The mai…

This study tests whether combining a medication (methylphenidate) with a non-invasive brain stimulation technique (iTBS) can reduce apathy in people with Alzheimer's or mixed dementia. Apathy, or lack of motivation, is common in these conditions. The trial involves 12 participant…

This study looks at whether adding electroconvulsive therapy (ECT) to usual care can safely reduce severe agitation in people with moderate to severe dementia, including Alzheimer's and other types. About 50 participants will receive ECT sessions along with their standard treatme…