ALLERGIC RHINITIS

This early-stage study tests a new drug called cizutamig in about 20 adults with IgE-mediated allergies, including food allergies. The main goal is to see if the drug can safely lower IgE levels, which are antibodies that trigger allergic reactions. Researchers will also monitor …

This early-phase trial is testing whether inhaling tiny particles from stem cells (called small extracellular vesicles) can safely help people with both allergic rhinitis and asthma. About 18 adults will receive either the active treatment or a placebo via nebulizer daily for two…

This study aims to find the best concentration of Blomia tropicalis (a type of dust mite) extract for allergy skin testing. About 30 adults with known dust mite allergies will receive small pricks with different extract strengths to see which causes a reaction similar to a standa…

This study looks at how well RHINOSEDAL works for people aged 8 and older with a stuffy nose caused by colds, allergies, or sinus issues. About 126 participants will use the treatment as prescribed and report their symptoms over 6 days. The goal is to see if it provides meaningfu…

This study tests a new nasal spray called PL-14 Allergy Blocker in about 120 adults with seasonal allergies. Unlike regular allergy sprays, PL-14 is drug-free and works by forming a gel-like barrier in the nose to block allergens. The study compares it to a simple saline spray ov…

This study looks at whether removing the adenoids (with or without tonsils) can improve allergy symptoms in children aged 3 to 12 who also have enlarged adenoids and tonsils. Researchers will compare surgery to standard medication by tracking symptom scores and allergy markers in…

This study compares two ways to treat moderate to severe allergic rhinitis: using a nasal steroid spray plus an antihistamine nasal spray versus the same steroid spray plus an antihistamine pill. Fifty people aged 12 to 75 will be randomly assigned to one of the two treatments fo…

This study tests whether giving extra booster shots of allergy medicine directly into the tonsils can better control hay fever symptoms. About 276 adults with allergic rhinitis will receive either the standard three doses or additional boosters. Researchers will track symptom rel…

This study looks at how well a saltwater (saline) nasal spray works and how safe it is for infants and toddlers aged 3 months to 4 years with stuffy noses from colds, flu, or allergies. About 83 children will use the spray for up to 14 days, and parents will report symptom change…

This study uses artificial intelligence to understand how air pollution and climate change impact respiratory diseases like allergic rhinitis and asthma. Researchers will gather health data from about 1,900 patients across Europe and analyze it with AI tools to find better ways t…