ALCOHOL MISUSE

This trial tests whether an AI chatbot called MICA, combined with weekly text reminders, can help emergency department patients reduce risky alcohol use. About 750 adults who report heavy drinking will be randomly assigned to use MICA or receive usual care. The study tracks how m…

This study will test a Spanish-language program called Healthy Choices for 45 young adults (ages 18-29) living with HIV in the Dominican Republic who also struggle with alcohol use and stigma. The program is designed to help them better manage their health and reduce the impact o…

This study tests whether taking cannabidiol (CBD) every night for four weeks can improve sleep quality and reduce alcohol cravings and use. Fifty-eight adults with poor sleep and hazardous drinking will take either CBD or a placebo. Participants will wear activity monitors, compl…

This study tests a mindfulness program designed to help sexual assault survivors reduce alcohol misuse and tobacco use. Researchers will enroll 120 college students aged 18-24 who have experienced sexual violence and drank alcohol recently. Participants will take online surveys a…

This study is testing a short behavioral treatment for women veterans who drink too much. The treatment involves 4 to 6 sessions with a behavioral health provider in a primary care clinic. Researchers want to see if it is practical, acceptable, and helps reduce alcohol use and im…

This pilot study will test a new type of talk therapy called ACT-SHARE for veterans who have both PTSD and alcohol problems and are struggling with conflict in their romantic relationships. The therapy aims to help veterans manage difficult thoughts and feelings and take actions …

This study looks at whether a blood test for a marker of heavy drinking (carbohydrate-deficient transferrin, or CDT) can help predict how well critically ill patients will do in the intensive care unit. Researchers will follow 800 adults admitted to the ICU through the emergency …

This study aims to improve a short motivational conversation to help young adults (ages 18-25) who were injured in an assault and also misuse alcohol or cannabis. Researchers will interview and survey 50 participants from a hospital violence intervention program to understand how…

This study will interview clinical staff and review patient data from an NHS alcohol care service in North West England. Researchers want to understand how acceptable the psychosocial interventions are to staff and what social or economic factors affect whether patients engage wi…

This study looks at whether sharing results from a blood test that shows recent alcohol use can help people with HIV drink less. Researchers will enroll 80 people in Uganda who drink heavily. Half will get standard counseling plus their blood test results, and half will get couns…

This study tests whether a mobile app-based program called mSTARS is practical and well-liked by adults who drink heavily and have recently been hospitalized for suicidal thoughts or behaviors. Thirty-five participants will be randomly assigned to the app, standard care, or stand…

This study looks at whether a program called SBIRT (Screening, Brief Intervention, and Referral to Treatment) can be used in hospitals to help teenagers with chronic medical conditions who may be misusing alcohol. Researchers will work with hospital staff, teens, and parents to a…