ALCOHOL ABUSE

This study tests an adaptive web-based program called Partners Connect for military couples. It aims to reduce drinking in concerned partners and encourage service members to seek help for alcohol use. About 744 couples will be assigned to either the online program or standard we…

This study tests a program called Mlambe for married couples in Malawi where one partner drinks heavily and both are affected by HIV. The program offers savings accounts, money management lessons, and relationship skills training to help couples reduce alcohol use and improve com…

This study tests a program called Kisoboka for men living with HIV who drink heavily in fishing communities. The goal is to help them drink less, take their HIV medication as prescribed, and reach undetectable viral loads. About 716 men will take part and be followed for 12 month…

This study tests a non-invasive brain stimulation device called Deep TMS to see if it can reduce heavy drinking in people with moderate to severe alcohol use disorder. About 186 adults aged 18-86 will receive either real or fake (sham) stimulation over several weeks. The goal is …

This study tests whether psilocybin or ketamine, combined with talk therapy, can help people with moderate to severe alcohol use disorder drink less. Eighty adults who have at least 4 heavy drinking days per month will receive either psilocybin or ketamine in a controlled setting…

This study tests if a program called Bright Horizons can help prevent binge drinking and drug use in Native American teens aged 12-17. The program teaches skills like managing emotions, coping with stress, and setting goals. Researchers will track changes in alcohol use over 30 d…

This study tests a small device that sends mild electrical pulses to a nerve in the ear to help people with alcohol use disorder manage withdrawal symptoms. Twenty adults will wear the device for 5 days during detox, and half will receive a placebo version. Researchers will measu…