ALCOHOL ABUSE

This study tests a device that uses magnetic pulses to stimulate the brain (Deep TMS) to help people with moderate to severe alcohol use disorder drink less. About 186 adults aged 18-86 will get either real or fake (sham) treatment over several weeks. The goal is to see if the re…

This study tests a program called Mlambe for married couples in Malawi where one partner drinks heavily and both are affected by HIV. The program offers savings accounts, money management classes, and relationship skills training to help couples reduce alcohol use. Researchers wi…

This study tests a program called Kisoboka for men living with HIV who drink heavily in fishing communities. The goal is to help them drink less, take their HIV medication as prescribed, and achieve undetectable viral loads. About 716 men will be randomly assigned to different co…

This study tests an adaptive web-based program called Partners Connect for military couples. It aims to reduce drinking in concerned partners and encourage service members to seek help for alcohol use. About 744 couples will participate, comparing the online program to standard w…

This study tests whether a single dose of psilocybin or ketamine, combined with talk therapy, can help people with moderate to severe alcohol use disorder drink less. Eighty adults who have at least four heavy drinking days per month will be randomly assigned to receive either ps…

This study tests whether a program called Bright Horizons can help prevent binge drinking and drug use in Native American youth aged 10 to 24. The program teaches skills like managing emotions, coping with stress, and setting goals. Researchers will compare it to standard case ma…

This study tests a wearable earpiece that gently stimulates nerves to help people going through alcohol withdrawal. Twenty adults with alcohol use disorder will wear the device or a sham version for 5 days during detox. Researchers will measure withdrawal severity, cravings, and …