AL AMYLOIDOSIS
Clinical trials for AL AMYLOIDOSIS explained in plain language.
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New hope for keeping rare blood disease in check after initial treatment
Disease control OngoingThis study is testing whether a maintenance therapy with the drug Ixazomib can help control AL amyloidosis and prevent it from coming back after patients have already responded to their first treatment. It involves 17 adults who have achieved at least a partial response to their …
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Gentle treatment tested for dangerous blood disorder
Disease control OngoingThis early-stage study is testing a new, cautious treatment strategy for patients with high-risk AL amyloidosis, a serious disease where abnormal proteins damage organs. Doctors are slowly adding different drugs, starting with isatuximab, to find the most effective combination pa…
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New hope for Tough-to-Treat amyloidosis: testing a powerful drug trio
Disease control OngoingThis study is testing whether adding a drug called pomalidomide to two other medications (daratumumab and dexamethasone) works better for people with AL amyloidosis that has come back or stopped responding to prior treatment. It is for patients who have already received daratumum…
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE2 • Sponsor: Weill Medical College of Cornell University • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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New antibody trial aims to help patients with rare, deadly organ disease live longer
Disease control OngoingThis study is testing whether adding an experimental antibody called CAEL-101 to standard treatment helps people with advanced AL amyloidosis. AL amyloidosis is a rare disease where abnormal proteins build up in organs like the heart, causing serious damage. The research will see…
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE3 • Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 09, 2026 14:24 UTC
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New antibody aims to clear deadly protein clogs from Patients' hearts and organs
Disease control OngoingThis study is testing whether adding an experimental antibody called CAEL-101 to standard treatment helps people with a serious stage of AL amyloidosis, a disease where abnormal proteins build up and damage organs like the heart. The antibody is designed to help clear these harmf…
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE3 • Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Mar 02, 2026 15:24 UTC
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New drug aims to ease harsh recovery for older cancer patients
Symptom relief OngoingThis study is testing if a drug called siltuximab can reduce the severe fatigue, pain, and nausea that often follow a stem cell transplant. It focuses on patients aged 60-75 with multiple myeloma or AL amyloidosis. The goal is to block a specific protein linked to inflammation, a…
Matched conditions: AL AMYLOIDOSIS
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated Mar 25, 2026 14:07 UTC