Aggressive B-cell lymphoma
Clinical trials for Aggressive B-cell lymphoma explained in plain language.
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New drug combo aims to boost lymphoma treatment
Disease control OngoingThis early-stage study tests whether adding either iberdomide or CC-99282 to standard chemotherapy (R-CHOP) can safely treat people with untreated aggressive B-cell lymphoma. About 224 adults will take part. The main goals are to find the best dose and check for side effects, whi…
Matched conditions: AGGRESSIVE B-CELL LYMPHOMA
Phase 1 • Sponsor: Celgene • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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New Chemo-Light cocktail offers hope for elderly lymphoma patients
Disease control OngoingThis phase 2 trial tests a chemotherapy-light combination of three drugs—rituximab, polatuzumab vedotin, and glofitamab—in 125 patients over 60 with aggressive B-cell lymphoma who cannot tolerate full-dose standard chemo. The goal is to see if this gentler approach can control th…
Matched conditions: AGGRESSIVE B-CELL LYMPHOMA
Phase 2 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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New hope for tough lymphomas: experimental drug shows promise in Mid-Stage trial
Disease control OngoingThis study tests an experimental drug called valemetostat tosylate in people with B-cell lymphoma whose cancer has returned or not responded to prior treatments. About 141 participants will receive the drug to see if it can shrink tumors. The goal is to find a new option for hard…
Matched conditions: AGGRESSIVE B-CELL LYMPHOMA
Phase 2 • Sponsor: The Lymphoma Academic Research Organisation • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC