New hope for tough lymphomas: experimental drug shows promise in Mid-Stage trial

NCT ID NCT04842877

First seen Feb 23, 2026 · Last updated Jun 18, 2026 · Updated 22 times

Summary

This study tests an experimental drug called valemetostat tosylate in people with B-cell lymphoma whose cancer has returned or not responded to prior treatments. About 141 participants will receive the drug to see if it can shrink tumors. The goal is to find a new option for hard-to-treat lymphomas.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • A.Z. Sint Jan AV

    Bruges, 8000, Belgium

  • CH Tourelle Peltzer

    Verviers, 4800, Belgium

  • CH d'Avignon

    Avignon, 84000, France

  • CH de la Côte Basque

    Bayonne, 64109, France

  • CHU Hôtel Dieu

    Nantes, 44093, France

  • CHU Mont-Godinne

    Yvoir, Belgium

  • CHU Pontchaillou

    Rennes, 35003, France

  • CHU d'Estaing

    Clermont-Ferrand, 63000, France

  • CHU de Dijon

    Dijon, 21034, France

  • CHU de Montpellier

    Montpellier, 34295, France

  • Ch Metropole Savoie - Site Chambery

    Chambéry, 73000, France

  • Ch de Bretagne Atlantique -

    Vannes, 56017, France

  • Chd de Vendee

    La Roche-sur-Yon, 85925, France

  • Clinique Victor Hugo

    Le Mans, 72000, France

  • Emmanuel Bachy

    Pierre-Bénite, 69495, France

  • François Lemonnier

    Créteil, 94010, France

  • Gh Region Mulhouse Et Sud Alsace

    Mulhouse, 68070, France

  • Institut Bergonié

    Bordeaux, 33076, France

  • Institut Paoli Calmette

    Marseille, 13273, France

  • Institut d'Hématologie de Basse Normandie

    Caen, 14076, France

  • Service des Maladies du Sang - CHRU de Lille

    Lille, 59037, France

  • University Hospital Gent

    Ghent, 9000, Belgium

Conditions

The condition(s) this trial relates to.

aggressive B-cell non-Hodgkin lymphoma B-cell neoplasm follicular lymphoma Hodgkins lymphoma indolent B-cell non-Hodgkin lymphoma mantle cell lymphoma marginal zone lymphoma Recurrence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.