AGE-RELATED MACULAR DEGENERATION (AMD)
Clinical trials for AGE-RELATED MACULAR DEGENERATION (AMD) explained in plain language.
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Could a multiple sclerosis drug protect eyesight in Age-Related macular degeneration?
Disease control Recruiting nowThis study tests whether an oral medication called dimethyl fumarate (Tecfidera), already used for multiple sclerosis, can safely slow the growth of geographic atrophy—a severe form of age-related macular degeneration that causes blind spots. About 90 adults aged 55–85 with geogr…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 17, 2026 01:50 UTC
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New drug combo aims to halt blind spot growth in dry AMD
Disease control Recruiting nowThis study tests two experimental drugs, pozelimab and cemdisiran, to see if they can slow the growth of blind spots (geographic atrophy) in people with advanced dry age-related macular degeneration (AMD). About 975 participants will receive either the drugs or a placebo by injec…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Phase: PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated May 17, 2026 01:45 UTC
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Tiny telescope implant offers new hope for AMD patients with severe vision loss
Disease control Recruiting nowThis study tests a small telescope implant (SING IMT) for people with advanced age-related macular degeneration (AMD) who have severe central vision loss in both eyes. Participants must be 55 or older, have had cataract surgery at least 6 months prior, and have stable vision. The…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Phase: NA • Sponsor: VisionCare, Inc. • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New eye drug aims to halt blinding disease in older adults
Disease control Recruiting nowThis study tests an experimental eye injection called ONL1204 in 324 adults aged 55 and older with geographic atrophy, a leading cause of blindness. The goal is to see if it can slow the growth of damaged areas in the retina and preserve vision. Participants will receive either t…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Phase: PHASE2 • Sponsor: ONL Therapeutics • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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AI eye check in family clinics could save sight for thousands
Diagnosis Recruiting nowThis study tests whether using an AI tool (VeriSee) during regular checkups can help find two common eye diseases—diabetic retinopathy and age-related macular degeneration—earlier than standard exams. About 4,300 adults with diabetes or aged 50+ will be randomly assigned to eithe…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Phase: NA • Sponsor: National Taiwan University Hospital • Aim: Diagnosis
Last updated Apr 30, 2026 15:49 UTC
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Veterans with vision loss pedal toward better health in new study
Symptom relief Recruiting nowThis study tests whether a 6-month online spin cycling program can improve vision, physical, and cognitive function in Veterans aged 65-89 with intermediate age-related macular degeneration (AMD). AMD is a leading cause of vision loss, and there are few treatments. Researchers wi…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 06, 2026 16:07 UTC
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New eye tests could speed up AMD treatment research
Knowledge-focused Recruiting nowThis study looks at new ways to measure how well the eye adapts to darkness in people with early age-related macular degeneration (AMD) and in healthy volunteers. The goal is to find reliable tests that can be used in future treatment trials. Researchers will track changes over t…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Sponsor: Maximilian Pfau • Aim: Knowledge-focused
Last updated May 17, 2026 01:47 UTC
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Scientists hunt for protein signs to spot eye diseases earlier
Knowledge-focused Recruiting nowThis study looks for specific proteins in blood and eye fluids that could help doctors better detect and understand age-related macular degeneration, diabetic retinopathy, and retinal detachment. About 260 adults with these conditions, plus healthy volunteers, will provide sample…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Phase: NA • Sponsor: Fondazione G.B. Bietti, IRCCS • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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New study tracks early eye fluid changes with High-Dose eylea
Knowledge-focused Recruiting nowThis study watches how the eyes of 50 people with wet age-related macular degeneration respond to a higher dose (8mg) of the drug Eylea during the first two months. Researchers use eye scans to measure fluid changes and vision improvements. The goal is to understand early treatme…
Matched conditions: AGE-RELATED MACULAR DEGENERATION (AMD)
Sponsor: Insel Gruppe AG, University Hospital Bern • Aim: Knowledge-focused
Last updated May 11, 2026 20:49 UTC