New eye injection aims to halt blindness from dry AMD in major trial

NCT ID NCT06659445

Recruiting now Disease control Sponsor: ONL Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 4 times

Summary

This study tests an experimental drug called ONL1204, given as an eye injection, to see if it can slow the growth of blind spots in people with geographic atrophy, an advanced form of dry age-related macular degeneration. About 324 adults aged 55 and older will receive either the drug or a sham injection. The goal is to preserve vision and prevent further damage to the retina.

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Conditions

The condition(s) this trial relates to.

age-related macular degeneration dry age related macular degeneration Geographic Atrophy macular degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Associated Retina Consultants
RECRUITING

Gilbert, Arizona, 85297, United States
Associated Retina Consultants
RECRUITING

Phoenix, Arizona, 85020, United States
Associated Retinal Consultants, P.C.
RECRUITING

Royal Oak, Michigan, 48073, United States
Associated Retinal Consultants, P.C.
RECRUITING

Traverse City, Michigan, 49686, United States
Austin Retina Associates
RECRUITING

Austin, Texas, 78705, United States
Bay Area Retina Associates
RECRUITING

Walnut Creek, California, 94598, United States
California Retina Consultants
RECRUITING

Bakersfield, California, 93309, United States
Charleston Neuroscience Institute
RECRUITING

Mt. Pleasant, South Carolina, 29464, United States
Cleveland Clinic Foundation-Cole Eye Institute
RECRUITING

Cleveland, Ohio, 44195, United States
Clinique d'ophtalmologie des Laurentides
RECRUITING

Boisbriand, Quebec, J7H0E8, Canada
Desert Retina Consultants
RECRUITING

Palm Desert, California, 92211, United States
Duke Eye Center
RECRUITING

Durham, North Carolina, 27710, United States
Erie Retina Research, LLC (Clinic)
RECRUITING

Erie, Pennsylvania, 16505, United States
Florida Retina Institute
RECRUITING

Orlando, Florida, 32806, United States
Illinois Retina Associates, S.C.
RECRUITING

Oak Park, Illinois, 60304, United States
Long Island Vitreoretinal Consultants
RECRUITING

Westbury, New York, 11590, United States
Macula and Retina Institute
RECRUITING

Glendale, California, 91203, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
North Carolina Retina Associates
RECRUITING

Cary, North Carolina, 27511, United States
North Carolina Retina Associates
RECRUITING

Greenville, North Carolina, 27834, United States
North Carolina Retina Associates, S.C.
RECRUITING

Wake Forest, North Carolina, 27587, United States
Northwestern Medical Group
RECRUITING

Chicago, Illinois, 60611, United States
Ophthalmic Consultants of Long Island
RECRUITING

Oceanside, New York, 11572, United States
Pacific Northwest Retina
RECRUITING

Bellevue, Washington, 98004, United States
Pacific Northwest Retina, PLLC
RECRUITING

Silverdale, Washington, 98383, United States
Palmetto Retina Center
RECRUITING

West Columbia, South Carolina, 29169, United States
Piedmont Eye Center
RECRUITING

Lynchburg, Virginia, 24502, United States
Retina Associates of Florida, LLC
RECRUITING

Tampa, Florida, 33609-4614, United States
Retina Associates of South Texas, PA
RECRUITING

San Antonio, Texas, 78240, United States
Retina Associates of Western NY
RECRUITING

Rochester, New York, 14620, United States
Retina Associates, Ltd.
RECRUITING

Elmhurst, Illinois, 60126, United States
Retina Center of Texas
RECRUITING

Southlake, Texas, 76092, United States
Retina Consultants of Southern Colorado
RECRUITING

Colorado Springs, Colorado, 80909-1183, United States
Retina Consultants of Texas
RECRUITING

Beaumont, Texas, 77707, United States
Retina Consultants of Texas
RECRUITING

Bellaire, Texas, 77401, United States
Retina Consultants of Texas
RECRUITING

Katy, Texas, 77494, United States
Retina Consultants of Texas
RECRUITING

San Antonio, Texas, 78240, United States
Retina Consultants of Texas
RECRUITING

The Woodlands, Texas, 77384, United States
Retina Group of Florida
RECRUITING

Sarasota, Florida, 34232, United States
Retina Group of New England
RECRUITING

Waterford, Connecticut, 06385, United States
Retina Partners Midwest, P.C.
RECRUITING

Carmel, Indiana, 46032, United States
Retina Research Institute at New England Retina Consultants
RECRUITING

Springfield, Massachusetts, 01107, United States
Retina Specialists
RECRUITING

Towson, Maryland, 21204, United States
Retina Specialty Institute
RECRUITING

Pensacola, Florida, 32503, United States
Retina Vitreous Surgeons of CNY, PC
RECRUITING

Liverpool, New York, 13088, United States
Retina-Vitreous Associates Medical Group
RECRUITING

Beverly Hills, California, 90211, United States
Retinal Consultants Medical Group
RECRUITING

Sacramento, California, 95841, United States
Salehi Retina Institute, dba Retina Associates of Southern California
RECRUITING

Huntington Beach, California, 92647, United States
Sierra Eye Associates
RECRUITING

Reno, Nevada, 89502, United States
St. Joseph's Health Care London - Ivey Eye Institute
RECRUITING

London, Ontario, N6A4V2, Canada
The Retina Institute
RECRUITING

St Louis, Missouri, 63128, United States
The University of Chicago Medicine Duchossois Center for Advanced Medicine
RECRUITING

Chicago, Illinois, 60637, United States
Toronto Retina Institute
RECRUITING

Toronto, Ontario, M3C0G9, Canada
Toronto Western Hospital, University Health Network
RECRUITING

Toronto, Ontario, M5T 2S8, Canada
University of Michigan Kellogg Eye Center
RECRUITING

Ann Arbor, Michigan, 48105, United States
Valley Retina Institute, P.A.
RECRUITING

McAllen, Texas, 78503, United States
Vanderbilt Eye Institute
RECRUITING

Nashville, Tennessee, 37232, United States

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