ACUTE MYELOID LEUKEMIA (AML)

This study tested whether adding a new drug called venetoclax to a standard low-dose chemotherapy (LDAC) works better than the low-dose chemo alone. It involved 211 adults with a new diagnosis of acute myeloid leukemia (AML) who were too old or had other health problems that made…

This study observed a standardized stem cell transplant procedure for adults with acute myeloid leukemia (AML) who were in remission. It aimed to see if using the same pre-transplant treatment worked well for transplants from three different donor types: matched siblings, matched…

This study tested whether adding a new drug called gilteritinib to standard azacitidine treatment helps adults with a specific type of acute myeloid leukemia (AML) live longer. It focused on older adults or those with other health problems who could not tolerate strong chemothera…

This early-stage study tested a new drug called PRT2527, both by itself and combined with other cancer drugs, in people with advanced blood cancers that had returned or stopped responding to standard treatments. The main goals were to find a safe dose and see if the treatments sh…

This study observed 113 Italian adults with specific aggressive forms of acute myeloid leukemia (AML) who were starting treatment with Vyxeos liposomal in their normal medical care. The goal was to see how well the treatment worked in real-world practice, focusing on achieving de…

This study tested whether adding a new drug called pevonedistat to a standard two-drug combination works better for adults newly diagnosed with acute myeloid leukemia (AML) who are too frail for intensive chemotherapy. About 164 participants worldwide were randomly assigned to re…

This study observed how a specific drug combination affects the quality of life and daily reality for older adults with a certain type of acute myeloid leukemia (AML) who cannot tolerate standard chemotherapy. Researchers followed 8 patients in Germany to see how they felt and fu…

This study collected real-world information from 112 patients in France with acute myeloid leukemia (AML) who were in remission. It aimed to understand how well an oral maintenance drug called azacitidine works to prevent the cancer from coming back and to describe the patients' …

This pilot study tested a combined transplant from a partially matched family donor. It aimed to treat patients who had both a serious blood disorder (like leukemia) and advanced kidney disease at the same time. The goal was to cure the blood disorder and restore kidney function …

This study monitored the safety and effectiveness of the approved leukemia drug venetoclax in real-world patients with acute myeloid leukemia (AML) in South Korea. About 150 adult patients who were prescribed the drug for the first time were observed for about 7 months during the…