ACUTE KIDNEY INJURY DUE TO SEPSIS
Clinical trials for ACUTE KIDNEY INJURY DUE TO SEPSIS explained in plain language.
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Experimental enzyme shot aims to rescue kidneys in sepsis patients
Disease control CompletedThis study tested a single intravenous dose of TIN816, an enzyme that breaks down ATP to reduce inflammation, in 316 ICU patients with sepsis-related acute kidney injury. The goal was to see if it improves kidney function over 8 days and reduces major kidney problems by day 90. T…
Matched conditions: ACUTE KIDNEY INJURY DUE TO SEPSIS
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Scientists hunt for clues to kidney damage in sepsis
Knowledge-focused CompletedThis completed study looked at 211 people with sepsis, some of whom also had acute kidney injury. Researchers measured specific microRNAs and other markers in the blood to understand how kidney damage happens. The goal was to find new targets for diagnosis or treatment, not to te…
Matched conditions: ACUTE KIDNEY INJURY DUE TO SEPSIS
Sponsor: University Hospital Ostrava • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Can a simple drug help predict kidney trouble in sepsis?
Knowledge-focused CompletedThis completed study from Indonesia University looked at 40 ICU patients with sepsis-related acute kidney injury. Researchers compared those who received the diuretic furosemide to a control group, measuring a protein called pNGAL in the blood as a marker of kidney damage. The go…
Matched conditions: ACUTE KIDNEY INJURY DUE TO SEPSIS
Phase: NA • Sponsor: Indonesia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New drug TIN816 tested for sepsis kidney damage
Knowledge-focused CompletedThis study tested an experimental drug called TIN816 in 20 adults in the intensive care unit who had kidney injury from sepsis. The main goal was to learn how the drug behaves in the body and whether it is safe. This was an early-stage study, so it focused on gathering informatio…
Matched conditions: ACUTE KIDNEY INJURY DUE TO SEPSIS
Phase: PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC