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Vaginismus
MONDO:0021723Tightness of the vaginal wall during vaginal penetration including sexual intercourse. It is caused by involuntary spasm of the pelvic floor muscles, and results in painful intercourse or failure to have intercourse. It may due to psychological conditions, trauma in the vaginal area, or vaginal infection.
Also known as: myalgia of pelvic floor, vaginismus
8 clinical trials for this condition and its sub-types.
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Broader categories
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Quick therapy after rape may stop PTSD before it starts
Prevention OngoingThis study tests whether a short, modified exposure therapy given soon after rape can prevent post-traumatic stress disorder (PTSD) in women. About 166 women who have experienced sexual assault will be randomly assigned to either the brief therapy or standard care. The goal is to…
Phase: NA • Sponsor: St. Olavs Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:30 UTC
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Can virtual reality help women overcome vaginismus?
Symptom relief OngoingThis study is testing whether virtual reality exposure therapy can help people with vaginismus, a condition where the pelvic floor muscles tighten involuntarily, making vaginal penetration painful or impossible. The idea is that gradually facing feared situations in a safe virtua…
Phase: NA • Sponsor: University of British Columbia • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Resident's journey to master scarless hysterectomy under the microscope
Knowledge-focused OngoingThis study watches a single gynecology resident as they learn to perform a hysterectomy through the vagina using a special camera, leaving no belly scars. The goal is to see how quickly the resident improves, measuring surgery time and any complications. Nineteen women with benig…
Sponsor: Cukurova University • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New biobank aims to unlock secrets of infertility and pregnancy
Knowledge-focused ENROLLING_BY_INVITATIONThis study is creating a biobank—a collection of blood samples and health data—to help researchers better understand gynecological disorders, infertility in men and women, and pregnancy-related conditions. Up to 3,000 participants will provide samples at San Raffaele Hospital in …
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC