Uremia

This study tests a special dialysis machine, the MultiFiltratePRO, in children with acute kidney failure. The goal is to see if it can deliver at least 80% of the prescribed treatment within 72 hours while being safe. About 43 children weighing between 8 and 40 kilograms will be …

This study tests whether a new intravenous drug, Anrikefon, can improve sleep quality better than a standard oral medication (nalfurafine) in people with chronic kidney disease who suffer from severe itching and are on hemodialysis. Fifty adults will receive either Anrikefon inje…

This study will observe 50 children (ages 1 month to 18 years) who come to the emergency room with kidney-related symptoms like swelling, blood in urine, or high blood pressure. Researchers want to learn which kidney diseases are most common and how children respond to initial tr…

This study tests whether shorter or standard-length dialysis sessions using expanded hemodialysis can remove waste products from the blood as well as a more intensive technique called high-volume hemodiafiltration. Fifteen adults with end-stage kidney disease will try three diffe…

This study will collect blood samples from 30,000 adults in the UK with various health conditions, including blood clots, infections, heart disease, diabetes, and more. The samples will be used to develop and fine-tune new diagnostic tests for the cobas® lumira device, which allo…

This observational study tests whether tiny chemicals in breath, called VOCs, can show if a hemodialysis session is effective. About 22 dialysis patients and 23 healthy adults will provide breath and blood samples. The goal is to find a simple, non-invasive way to assess dialysis…