Univentricular cardiopathy

This study looked at the long-term safety of udenafil in 301 adolescents with single ventricle heart disease who had Fontan surgery. Participants took the drug for 52 weeks. The main goal was to track side effects, with secondary measures including exercise capacity and blood ves…

This study tested whether the drug udenafil can reduce liver stiffness in 88 children with single ventricle heart disease, a condition where the heart has only one pumping chamber. Participants took udenafil twice daily for 52 weeks, and liver stiffness was measured using ultraso…

This study tests a two-part virtual program for teens aged 13-18 with Fontan physiology, a type of single-ventricle heart disease. The first part is a small-group wellness education session each week for 5 weeks, led by a psychologist. The second part is a personalized home exerc…

This study looks at how the heart medication digoxin is processed in infants born with single ventricle heart disease. Researchers will collect blood samples during routine care to measure drug levels. The goal is to better understand dosing, but the study does not change the inf…

This study looked at whether a small device called an implantable loop recorder can be safely placed in newborns who have only one working heart chamber. Ten babies received the monitor during their first heart surgery. The goal was to see if the device could continuously track h…