Tooth hard tissue disease
MONDO:0002220Also known as: disorder of hard tissues of teeth, teeth hard tissue disease, teeth hard tissue diseases
501 clinical trials for this condition and its sub-types.
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Broader categories
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A simple silver liquid may halt cavities in Toddlers—Without drilling
Disease control TerminatedThis trial tests whether a liquid called silver diamine fluoride (SDF) can stop cavities in baby teeth. About 830 children aged 12 months to 5 years with active cavities will receive either SDF or a placebo applied to their teeth twice, six months apart. Researchers will check if…
Phase: PHASE3 • Sponsor: University of Michigan • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New dental goo aims to save teeth from decay and trauma
Disease control TerminatedThis study tested a special dental material (Vitrebond) used to cover and protect the soft inner part of a tooth (the pulp) when it gets exposed due to deep cavities, injury, or dental work. The goal was to see if the material keeps the tooth alive and healthy for up to 5 years. …
Phase: NA • Sponsor: Solventum US LLC • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New dental crowns tested – but trial halted early
Disease control TerminatedThis study tested lithium disilicate crowns made with CAD/CAM technology in 8 adults with cavities or damaged teeth. The crowns were placed using different adhesive methods to check for sensitivity and quality. The trial was terminated early, so the findings are limited.
Phase: NA • Sponsor: Ivoclar Vivadent AG • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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New dental liner aims to ease Post-Filling tooth pain
Symptom relief TerminatedThis study tested a new dental liner called Vitrebond™ Pulp Protect Liner/Base, placed under fillings to reduce tooth sensitivity after treating decay. It included 5 people aged 7 and older with moderate to advanced tooth decay. The liner was compared to a similar existing produc…
Phase: NA • Sponsor: Solventum US LLC • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC