Tick-borne encephalitis
MONDO:0017572Tick-borne encephalitis is caused by an arbovirus of the Flaviviridae family (tick-borne encephalitis virus, TBEV), transmitted principally by the bite of the Ixodes ricinus tick. The symptomology is biphasic, with the initial phase being associated with a flu-like illness and the second phase (occurring in less than 10% of patients) with symptoms of meningitis or, more rarely, meningoencephalitis.
Also known as: TBE, Tick-borne viral encephalitis
15 clinical trials for this condition and its sub-types.
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Can a common steroid tame Tick-Borne brain infection?
Disease control Recruiting nowThis study tests whether the steroid dexamethasone can reduce brain damage in adults hospitalized with tick-borne encephalitis. Researchers will compare disability outcomes in 200 patients who receive either dexamethasone or a placebo. The goal is to see if this treatment lowers …
Phase: PHASE3 • Sponsor: University Medical Centre Ljubljana • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Could immune checkpoint drugs tame a deadly brain virus?
Disease control Recruiting nowThis study is testing whether immune checkpoint inhibitors, drugs that help the immune system fight infections, can improve outcomes for people with progressive multifocal leukoencephalopathy (PML), a rare brain virus. Researchers will follow 66 patients over a year, measuring di…
Sponsor: Peking Union Medical College Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Can donor cells stop viruses after transplant?
Disease control Recruiting nowThis study tests whether giving patients donor-derived immune cells (VSTs) on a regular schedule can prevent dangerous viral infections after a stem cell transplant. 180 participants will be randomly assigned to receive VSTs either on a fixed schedule or only when a virus is dete…
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Supercharged donor cells take on viruses after transplant
Disease control Recruiting nowThis study tests whether specially grown donor immune cells (viral-specific T-cells) can safely treat viral infections that often occur after a stem cell transplant. These infections can be serious and sometimes don't respond to standard antiviral drugs. The approach aims to boos…
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Scientists launch major study to track viruses in healthy and immunocompromised patients
Knowledge-focused Recruiting nowThis study aims to collect samples and medical information from people of all ages who have or have been exposed to viral infections, including COVID-19 and herpes. Researchers want to understand how viruses affect healthy individuals versus those with weakened immune systems. Pa…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Aug 09, 2026 00:00 UTC
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Swedish tick study aims to uncover hidden health threats
Knowledge-focused Recruiting nowThis study is tracking 600 children and adults in Sweden who may have tick-borne diseases. Researchers will monitor their health over six months to better understand symptoms, improve diagnosis, and develop clearer treatment guidelines. The goal is to help doctors manage these in…
Sponsor: Region Jönköping County • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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10,000 people tested: Cambodia's massive disease hunt begins
Knowledge-focused Recruiting nowThis study will test 10,000 people in Cambodia for 57 different infectious diseases, including dengue, flu, and malaria. Researchers want to understand how these diseases spread and who is at risk. The goal is to give local health authorities the information they need to create b…
Sponsor: Institut Pasteur du Cambodge • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New study tracks Tick-Borne brain infection recovery to improve patient care
Knowledge-focused Recruiting nowThis study follows 209 children and adults hospitalized with tick-borne encephalitis (TBE) in the Czech Republic for one year after discharge. Researchers track symptoms like fatigue, headaches, memory problems, and weakness to see how long they last and who needs extra support. …
Sponsor: Charles University, Czech Republic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Do french doctors know enough about Tick-Borne encephalitis? a new survey aims to find out
Knowledge-focused Recruiting nowThis study surveys 100 doctors and trainees in France to assess their knowledge of tick-borne encephalitis, a rare but serious viral infection spread by ticks. The goal is to see if doctors in high-risk areas are more aware than those elsewhere, and to identify gaps that could im…
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC