T2-low asthma
MONDO:0956976A chronic asthma that is characterized by the pathophysiology phenotype combination (endotype) of non-atopic, smoking, obesity related, and elderly and that is characterized by neutrophilic (sputum neutrophils > 40–60%) or paucigranulocytic (i.e., normal sputum levels of both eosinophils and neutrophils) inflammation and a lack of response to corticosteroid therapy.
6 clinical trials for this condition and its sub-types.
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Could a Mucus-Busting drug help Hard-to-Treat asthma?
Symptom relief CompletedThis small pilot study tested whether inhaling a drug called rhDNAse every day for 4 weeks could help adults with neutrophilic asthma, a type of asthma that often doesn't respond well to standard treatments. The drug works by breaking down DNA in lung mucus, making it thinner and…
Phase: PHASE1, PHASE2 • Sponsor: National Jewish Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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Could a tiny dose of muscle relaxant make lung scopes safer?
Symptom relief CompletedThis study looked at whether giving a low dose of a muscle relaxant (rocuronium) during bronchoscopy—a procedure where a tube is inserted into the lungs—could reduce complications like throat spasms and coughing. 153 adults having elective bronchoscopy were split into two groups:…
Phase: NA • Sponsor: Harbin Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC