Steroid-resistant nephrotic syndrome
MONDO:0044765Nephrotic syndrome, occurring in the pediatric population, in which proteinuria does not normalize with administration of steroids; this condition is unresponsive to a minimum of four weeks administration of oral corticosteroids.
Also known as: nephrotic syndrome of childhood - steroid resistant, nephrotic syndrome-steroid-resistant, steroid-resistant nephrotic syndrome, nephrotic syndrome, idiopathic, steroid-resistant, nephrotic syndrome, steroid-resistant, autosomal recessive, NPHS2, SRNS - steroid-resistant nephrotic syndrome, steroid-unresponsive nephrotic syndrome
16 clinical trials for this condition and its sub-types.
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Broader categories
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Can a common statin help kids with kidney disease and high cholesterol?
Disease control CompletedThis completed Phase 4 trial tested the drug atorvastatin (Lipitor) in 100 children aged 8-18 with steroid-sensitive nephrotic syndrome and high cholesterol. The goal was to see if the drug safely lowers cholesterol to healthy levels within 3 to 6 months. The study compared atorv…
Phase: PHASE4 • Sponsor: National Institute of Kidney Disease and Urology (NIKDU) • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Common antibiotic may speed remission in kids with kidney disease
Disease control CompletedThis study tested whether adding the antibiotic azithromycin to standard steroid treatment helps children with steroid-sensitive nephrotic syndrome achieve remission faster. 160 children aged 2 to 14 were split into two groups: one received azithromycin plus steroids, the other o…
Phase: PHASE1 • Sponsor: University of Child Health Sciences and Children's Hospital, Lahore • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Gene hunt for kidney disease FSGS aims to explain racial disparities
Knowledge-focused CompletedThis study searched for genetic factors that may cause focal segmental glomerulosclerosis (FSGS), a kidney disease that can lead to kidney failure. Researchers compared DNA from 616 people, including African-Americans with FSGS, African-Americans with HIV but no FSGS, and non-Afr…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Aug 18, 2026 02:00 UTC