Steroid-resistant nephrotic syndrome
MONDO:0044765Nephrotic syndrome, occurring in the pediatric population, in which proteinuria does not normalize with administration of steroids; this condition is unresponsive to a minimum of four weeks administration of oral corticosteroids.
Also known as: nephrotic syndrome of childhood - steroid resistant, nephrotic syndrome-steroid-resistant, steroid-resistant nephrotic syndrome, nephrotic syndrome, idiopathic, steroid-resistant, nephrotic syndrome, steroid-resistant, autosomal recessive, NPHS2, SRNS - steroid-resistant nephrotic syndrome, steroid-unresponsive nephrotic syndrome
25 clinical trials for this condition and its sub-types.
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Broader categories
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Can a common statin help kids with kidney disease and high cholesterol?
Disease control CompletedThis completed Phase 4 trial tested the drug atorvastatin (Lipitor) in 100 children aged 8-18 with steroid-sensitive nephrotic syndrome and high cholesterol. The goal was to see if the drug safely lowers cholesterol to healthy levels within 3 to 6 months. The study compared atorv…
Phase: PHASE4 • Sponsor: National Institute of Kidney Disease and Urology (NIKDU) • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Common antibiotic may speed remission in kids with kidney disease
Disease control CompletedThis study tested whether adding the antibiotic azithromycin to standard steroid treatment helps children with steroid-sensitive nephrotic syndrome achieve remission faster. 160 children aged 2 to 14 were split into two groups: one received azithromycin plus steroids, the other o…
Phase: PHASE1 • Sponsor: University of Child Health Sciences and Children's Hospital, Lahore • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Sweat sensor could replace needles for kidney patients
Diagnosis CompletedThis study tested a new wearable patch that collects sweat to measure sodium and creatinine levels, which are important for monitoring kidney health and dehydration. Five adults with kidney disease wore the patch while their sweat was analyzed using a special light-based techniqu…
Phase: NA • Sponsor: Korea University • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC
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Gene hunt for kidney disease FSGS aims to explain racial disparities
Knowledge-focused CompletedThis study searched for genetic factors that may cause focal segmental glomerulosclerosis (FSGS), a kidney disease that can lead to kidney failure. Researchers compared DNA from 616 people, including African-Americans with FSGS, African-Americans with HIV but no FSGS, and non-Afr…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC