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Skin pigmentation disorder
MONDO:0019288A pigmentation disease that involves the zone of skin.
Also known as: pigmentation anomaly of the skin, pigmentation disease of zone of skin, zone of skin pigmentation disease, pigmentation disease
63 clinical trials for this condition and its sub-types, 12 tagged with Skin pigmentation disorder itself.
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Sub-types of Skin pigmentation disorder
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Hyperpigmentation of the skin 17 trials · 31 incl. sub-types
24 sub-types
- Legius syndrome 5 trials
- Dowling-Degos disease 0 trials · 4 incl. sub-types Sub-types →
- Schwannomatosis 3 trials Sub-types →
- Dyschromatosis symmetrica hereditaria 1 trial
- Dyschromatosis universalis hereditaria 1 trial Sub-types →
- H syndrome 0 trials
- Naegeli-Franceschetti-Jadassohn syndrome 0 trials
- Acromelanosis 0 trials
- Cafe au lait spots, multiple 0 trials
- Dermatopathia pigmentosa reticularis 0 trials
- Extrasystoles-short stature-hyperpigmentation-microcephaly syndrome 0 trials
- Familial generalized lentiginosis 0 trials
- Familial progressive hyperpigmentation 0 trials Sub-types →
- Gastrocutaneous syndrome 0 trials
- Hyperkeratosis-hyperpigmentation syndrome 0 trials
- Hyperpigmentation, progressive cribriform and zosteriform 0 trials
- Leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome 0 trials
- Linear and whorled nevoid hypermelanosis 0 trials
- Mosaic Legius syndrome 0 trials
- Nail and teeth abnormalities-marginal palmoplantar keratoderma-oral hyperpigmentation syndrome 0 trials
- Osteopathia striata-pigmentary dermopathy-white forelock syndrome 0 trials
- Phakomatosis pigmentovascularis 0 trials Sub-types →
- Reticulate acropigmentation of Kitamura 0 trials
- Severe growth deficiency-strabismus-extensive dermal melanocytosis-intellectual disability syndrome 0 trials
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Hypopigmentation of the skin 2 trials · 21 incl. sub-types
10 sub-types
- Syndromic oculocutaneous albinism 0 trials · 12 incl. sub-types Sub-types →
- Oculocutaneous albinism 4 trials Sub-types →
- Piebaldism 4 trials
- Tietz syndrome 1 trial
- Ito hypomelanosis 0 trials
- Albinism-hearing loss syndrome 0 trials
- Deaf blind hypopigmentation syndrome, Yemenite type 0 trials
- Deafness, congenital, with total albinism 0 trials
- Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies 0 trials
- Piebald trait-neurologic defects syndrome 0 trials
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Reticulate pigment disorder 0 trials · 5 incl. sub-types
3 sub-types
- Dowling-Degos disease 0 trials · 4 incl. sub-types Sub-types →
- Dyschromatosis symmetrica hereditaria 1 trial
- Reticulate acropigmentation of Kitamura 0 trials
Most studied deeper sub-types
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Can a hormone drug help restore skin color in vitiligo?
Disease control Recruiting nowThis Phase 2 study tests whether adding Melanotan II (a synthetic hormone-like drug) to standard narrowband UV-B light therapy helps restore skin color in adults with stable nonsegmental vitiligo. About 60 participants will receive either the drug or a placebo, plus light therapy…
Phase 2 • Sponsor: Hudson Biotech • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Could almond oil beat a Skin-Lightening cream?
Symptom relief Recruiting nowThis study compares almond oil to hydroquinone cream for treating facial pigmentation in women with darker skin tones. Researchers will also check how each treatment affects the skin's microbiome. The goal is to see if almond oil is a safer, natural alternative to the standard tr…
Phase 4 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Sep 16, 2026 00:00 UTC
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Study reveals pulse oximeters may be less accurate for darker skin in kids with heart defects
Knowledge-focused Recruiting nowThis study looks at whether pulse oximeters—the clips placed on fingers to measure oxygen levels—work equally well for children with different skin tones who have congenital heart disease. Researchers will enroll 92 children under 18 undergoing heart surgery and compare the oxime…
Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Tiny study hopes to unlock genetic secrets of rare skin condition
Knowledge-focused Recruiting nowThis study is looking for the gene or genes that cause cutis tricolor, a rare skin condition with patches of different colors. Researchers will analyze DNA from blood and skin samples of 10 patients and their parents. The goal is to find genetic changes that might explain the con…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Can your pulse oximeter be trusted? new study tests accuracy across skin tones
Knowledge-focused Recruiting nowThis study checks how well pulse oximeters measure blood oxygen during mild to severe low oxygen levels in 10,000 healthy adults aged 18-50. Researchers compare the device's reading to a precise blood test, and also look at how skin pigmentation affects accuracy. The goal is to m…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:40 UTC