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Secondary malignant neoplasm
MONDO:0024881A malignant neoplasm that arises from a pre-existing lower grade lesion, or as a result of a primary lesion that has spread to secondary sites, or due to a complication of a cancer treatment.
Also known as: secondary cancer, secondary malignancy, secondary malignant neoplasm
3819 clinical trials for this condition and its sub-types, 27 tagged with Secondary malignant neoplasm itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Secondary malignant neoplasm
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Metastatic malignant neoplasm 748 trials · 1,265 incl. sub-types
7 sub-types
- Metastatic malignant neoplasm in the brain 267 trials
- Metastatic carcinoma 22 trials · 168 incl. sub-types Sub-types →
- Neoplastic meningitis 82 trials
- Metastatic malignant neoplasm in the spinal cord 38 trials
- Metastasis from malignant tumor of colon 27 trials
- Metastatic malignant neoplasm in the colon 18 trials
- Metastatic malignant neoplasm in the eye 1 trial
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Secondary carcinoma 1 trial · 169 incl. sub-types
1 sub-type
- Metastatic carcinoma 22 trials · 168 incl. sub-types Sub-types →
Most studied deeper sub-types
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New imaging tech aims to sharpen liver cancer radiation
Disease control OngoingThis study looks at whether a special imaging technique called KIM can help doctors deliver radiation more accurately to liver tumors. About 32 adults with liver cancer who cannot have surgery or a transplant will receive radiation with and without KIM tracking. The goal is to se…
Sponsor: University of Sydney • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Radiation combo aims to fight cancer without drugs – but study never started
Knowledge-focused CancelledThis study planned to test whether adding low-dose radiation to standard high-dose radiation could trigger an 'abscopal effect' – where untreated tumors also shrink. It was designed for adults with metastatic solid tumors. However, the study was withdrawn before any patients were…
Sponsor: Soonchunhyang University Hospital • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Does your income affect your cancer care? new study investigates
Knowledge-focused OngoingThis study analyzes data from over 45,000 people diagnosed with colon or ovarian cancer in England between 2016 and 2017. Researchers are looking for differences in how quickly people are diagnosed and what treatments they receive, based on their socioeconomic status. The goal is…
Sponsor: University of Hull • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Lung cancer Follow-Up: is Twice-Yearly CT better than once a year?
Knowledge-focused OngoingThis study follows over 1,800 adults who had early-stage lung cancer treatment to see how often they get CT scans and whether scanning every 6 months helps them live longer than yearly scans. Researchers will also check if scan frequency differs by race, income, or location. The …
Sponsor: University of Florida • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Electric shocks + chemo: new hope for liver tumors?
Knowledge-focused OngoingThis study is a registry that collects information on how well electrochemotherapy (ECT) works for people with liver cancer. ECT uses short electric pulses to help chemotherapy drugs enter cancer cells more effectively. The study will follow 250 adults with primary or secondary l…
Sponsor: Cardiovascular and Interventional Radiological Society of Europe • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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New test may reveal hidden cancer after liver ablation
Knowledge-focused OngoingThis study looks at tissue from liver tumors that were destroyed using heat or cold (ablation). The goal is to see if a special test on that tissue can tell whether the treatment fully killed the cancer, which standard CT scans cannot always do. About 150 people with liver cancer…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Stem cells may unlock mystery of chemo-related heart damage
Knowledge-focused OngoingThis study uses stem cells made from patients' own cells to understand why some people develop severe heart or lung side effects from certain chemotherapy drugs. Researchers will compare cells from patients who had extreme toxicity to those who did not. The goal is to uncover the…
Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC