Rabies

This study checks if a single rabies booster shot can still protect people who got their first rabies vaccine at least 5 years ago. About 561 healthy adults will get a booster, and researchers will measure their immune response after 7 days. The goal is to see if different initia…

This study compares two ways of giving the rabies vaccine: the standard shot in the muscle versus a smaller dose injected under the skin. Researchers want to see if the skin method works just as well and is as safe, while using less vaccine and costing less. About 90 healthy volu…

This study tests a new experimental rabies vaccine (ChAdOx2 RabG) given together with the standard rabies vaccine in healthy adults aged 18-45. The goal is to see if this combination is safe and produces a strong immune response, potentially allowing a single visit instead of the…

This study compares two common antibiotic combinations—vancomycin with piperacillin/tazobactam versus vancomycin with meropenem—to see which is less harmful to the kidneys. About 852 hospitalized adults with serious infections will be randomly assigned to one of the two combos. T…

This study tests a lab-made antibody injection designed to prevent rabies after exposure. About 200 healthy adults aged 18-60 will receive the injection to check its safety and how well it boosts rabies-fighting antibodies. The goal is to find a reliable treatment that can be use…

This study tests whether three different batches of a rabies vaccine work the same way and are safe. It involves 912 healthy adults aged 18 to 45. The goal is to make sure every batch produces a strong immune response.

This observational study will look at 10,000 adults in intensive care units (ICUs) around the world during a single 24-hour period. Researchers want to find out how common infections and antibiotic-resistant bacteria are, how they are treated, and how patients recover. No new tre…

This research project aims to understand why older adults get more infections and why those infections can be more serious. By following 23,000 people aged 60 and older, scientists will collect health data and samples like blood and stool to study how the immune system changes wi…

This study will collect blood samples from 30,000 adults in the UK with various health conditions, including blood clots, infections, heart disease, diabetes, and more. The samples will be used to develop and fine-tune new diagnostic tests for the cobas® lumira device, which allo…

This study will follow 300 adults with severe infections in the ICU to see how levels of specialized pro-resolving mediators (SPMs)—natural molecules that help stop inflammation—change over time. Researchers will use blood samples already collected during routine care, so no extr…