Pseudohypoaldosteronism type 1

A rare, primary form of mineralocorticoid resistance characterized by mild to profound salt wasting either restricted to the kidney (renal pseudohypoaldosteronism type 1), or generalized affecting many organs (generalized pseudohypoaldosteronism type 1). Clinical presentation is in the neonatal period with failure to thrive, vomiting and dehydration with biochemical findings of hyperkalaemia, metabolic acidosis and, elevated plasma aldosterone and renin concentration.

Also known as: PHA type 1, pseudohypoaldosteronism, type I, PHA1B, pseudohypoaldosteronism type I autosomal recessive

13 clinical trials for this condition and its sub-types.