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Pseudohypoaldosteronism type 1
MONDO:0019161A rare, primary form of mineralocorticoid resistance characterized by mild to profound salt wasting either restricted to the kidney (renal pseudohypoaldosteronism type 1), or generalized affecting many organs (generalized pseudohypoaldosteronism type 1). Clinical presentation is in the neonatal period with failure to thrive, vomiting and dehydration with biochemical findings of hyperkalaemia, metabolic acidosis and, elevated plasma aldosterone and renin concentration.
Also known as: PHA type 1, pseudohypoaldosteronism, type I, PHA1B, pseudohypoaldosteronism type I autosomal recessive
13 clinical trials for this condition and its sub-types.
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Sweat sensor could replace needles for kidney patients
Diagnosis CompletedThis study tested a new wearable patch that collects sweat to measure sodium and creatinine levels, which are important for monitoring kidney health and dehydration. Five adults with kidney disease wore the patch while their sweat was analyzed using a special light-based techniqu…
Phase: NA • Sponsor: Korea University • Aim: Diagnosis
Last updated Jun 27, 2026 08:11 UTC
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New antibiotic combo tested for safety in healthy volunteers
Knowledge-focused CompletedThis early-stage study tested the safety and how the body processes two antibiotics—Zidebactam-Cefepime and Metronidazole—given alone or together. Thirty healthy adults received single doses in three different sequences. The goal was to measure drug levels and check for side effe…
Phase: PHASE1 • Sponsor: Wockhardt • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:37 UTC